SCHEMBL29418231

SCHEMBL29418231

CC(O)C(N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CS)C(=O)O)C(C)O

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.62
▸ IL23R Q5VWK5 13/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29426546 1.00 TFPI (0.62) TFPIIL23R
SCHEMBL30577892 0.98 IL23R (0.62) TFPIIL23R
SCHEMBL29372983 0.97 TFPI (0.64) TFPIIL23R
SCHEMBL22807671 0.97 TFPI (0.64) TFPIIL23R
SCHEMBL30413638 0.96 IL23R (0.61) TFPIIL23R
SCHEMBL31504570 0.94 TFPI (0.67) TFPIIL23R
SCHEMBL30973957 0.94 TFPI (0.64) TFPIIL23R
SCHEMBL31031575 0.94 TFPI (0.64) TFPIIL23R
SCHEMBL30414074 0.94 TFPI (0.60) TFPIIL23R
SCHEMBL30577891 0.94 IL23R (0.63) TFPIIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746916-A2 CLEAVABLE POLYMER-DRUG CONJUGATES FOR ALZHEIMER'S DISEASE University of Utah Research Foundation (US) 2026-05-27 — — EP claimed
CN-121015904-B Method for regulating and controlling beta-amyloid aggregation based on circularly polarized light and application thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2026-05-26 — — CN claimed
EP-4554563-B1 REVERSED MICELLES FOR DELIVERY OF HYDROPHILIC DRUGS CONSIGLIO NAZ DELLE RICERCHE CNR (IT) 2026-02-25 — — EP claimed
US-20260007770-A1 REVERSED MICELLES FOR DELIVERY OF HYDROPHILIC DRUGS CONSIGLIO NAZIONALE RICERCHE (IT) 2026-01-08 — — US claimed
US-20250381277-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERS DANA FARBER CANCER INST INC (US) 2025-12-18 — — US claimed
US-20250332298-A1 PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES BLUE WAVE THERAPEUTICS GMBH (CH) 2025-10-30 — — US claimed
WO-2025201467-A1 POLYPEPTIDE OLIGONUCLEOTIDE CONJUGATE FOR INHIBITING EXPRESSION OF TARGET GENE IN CENTRAL NERVOUS SYSTEM AND USE THEREOF 广州必贝特医药股份有限公司 2025-10-02 — — WO claimed
EP-4611783-A1 GENE THERAPY CONSTRUCTS FOR METABOLIC DISORDERS Erasmus University Rotterdam Medical Center (NL) 2025-09-10 — — EP claimed
CN-120077136-A SiRNA and drug for inhibiting Amyloid Precursor Protein (APP) gene expression and application thereof 广州必贝特医药股份有限公司 2025-05-30 — — CN claimed
WO-2025104335-A1 MITOCHONDRIAL INTERVENTION IN NEUROLOGICAL DISORDERS RASSAF TIENUSH (DE) 2025-05-22 — — WO claimed
CN-117177747-A Targeted bifunctional degradants and methods of use thereof 耶鲁大学 2023-12-05 — — CN claimed
WO-2023225204-A1 METHOD FOR TREATING CANCER SUNTEC MEDICAL, INC. (US) 2023-11-23 — — WO claimed
CN-116999580-A Preparation method and application of polypeptide boron carrier radiopharmaceutical 北京大学深圳研究生院 2023-11-07 — — CN claimed
WO-2022178428-A9 TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME YALE UNIVERSITY (US) 2023-08-17 — — WO claimed
WO-2023150552-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERS DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-08-10 — — WO claimed
US-20230233689-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins UNIV YALE (US) 2023-07-27 — — US claimed
WO-2023066994-A1 PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES BLUE WAVE THERAPEUTICS GMBH (CH) 2023-04-27 — — WO claimed
US-20230083388-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins UNIV YALE (US) 2023-03-16 — — US claimed
US-11504394-B2 Targeted ionophore-based metal delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-11-22 — — US claimed
WO-2022178425-A1 TARGETED BIFUNCTIONAL DEGRADERS YALE UNIVERSITY (US) 2022-08-25 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233689-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins ASGR1, LDLR, FCGR2A TFPI 1162/4885IL23R 1101/4885
US-20260007770-A1 REVERSED MICELLES FOR DELIVERY OF HYDROPHILIC DRUGS ABCB11, ABCC1, ABCE1 TFPI 1132/4885IL23R 4054/4885
US-11504394-B2 Targeted ionophore-based metal delivery SLC8B1, SLC47A2, ATP2A2 TFPI 3878/4885IL23R 4738/4885
US-20230083388-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins ASGR1, LDLR, FCGR2A TFPI 1162/4885IL23R 1101/4885
US-20250332298-A1 PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES ALG1, ALG3, GRPR TFPI 4688/4885IL23R 891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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