Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359047 | 0.79 | PNMT (0.53) | PGRALDH1A1HPGDNPC1PNMT | |
| SCHEMBL17852147 | 0.79 | MAPK1 (0.39) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL30954660 | 0.79 | PRCP (0.40) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL30714854 | 0.79 | CA1 (0.41) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL9811064 | 0.76 | CA1 (0.47) | PGRALDH1A1HPGDHIF1ANPC1 | |
| SCHEMBL1655232 | 0.76 | MEN1 (0.46) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL5684576 | 0.76 | PGR (0.47) | PGRMAPK1PNMTNOS3NOS2 | |
| SCHEMBL29517854 | 0.76 | PGR (0.47) | PGRMAPK1PNMTNOS3NOS2 | |
| SCHEMBL30924248 | 0.76 | MEN1 (0.46) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL24727268 | 0.74 | PGR (0.50) | PGRALDH1A1HPGDNPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163301-A | Preparation method of benzo [ B ] fluorene derivative and derivative thereof | 陕西维世诺新材料有限公司 | 2022-03-11 | — | — | CN | disclosed |