Echinomycin

Echinomycin

SCHEMBL29420869

CS[C@H]1SC[C@H]2C(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)c3cnc4ccccc4n3)C(=O)N[C@@H](C)C(=O)N(C)[C@@H]1C(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)c1cnc3ccccc3n1)C(=O)N[C@@H](C)C(=O)N2C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Echinomycin SCHEMBL18506201 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL13464701 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL29529894 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL63091 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL30725384 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL18477111 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL13928604 1.00 RIPK1 (0.32) RIPK1
SCHEMBL20323949 0.96 RIPK1 (0.31) RIPK1
SCHEMBL12556535 0.95 RIPK1 (0.31) RIPK1
SCHEMBL29378829 0.95 RIPK1 (0.32) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106877-A1 INHALED HYPOXIA AND SMALL MOLECULE FORMS OF HYPOXIA AS NOVEL ANTICANCER AGENTS THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) 2025-05-22 WO claimed
CN-119552794-B Streptomyces glacialis with sbhR gene deleted and preparation method and application thereof 中国农业科学院植物保护研究所 2025-05-16 CN claimed
CN-119552794-A Streptomyces glacialis with sbhR gene deleted and preparation method and application thereof 中国农业科学院植物保护研究所 2025-03-04 CN claimed
EP-3868409-B1 THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS REMEGEN CO LTD (CN) 2024-07-17 EP claimed
US-11964019-B2 Cochleates made with soy phosphatidylserine RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-04-23 US claimed
US-20260116986-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS IMMUNEDGE INC (US) 2026-04-30 US disclosed
WO-2025231217-A1 COMPOSITIONS AND METHODS OF OLIGONUCLEOTIDE HITCHHIKING FOR ENCAPSULATION OF DRUGS IN LIPID NANOPARTICLES UNIVERSITY OF MARYLAND, BALTIMORE (US) 2025-11-06 WO disclosed
US-12409227-B2 Cochleates made with soy phosphatidylserine RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-09-09 US disclosed
WO-2025106877-A1 INHALED HYPOXIA AND SMALL MOLECULE FORMS OF HYPOXIA AS NOVEL ANTICANCER AGENTS THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) 2025-05-22 WO disclosed
US-20250146018-A1 COMPOSITIONS AND METHODS FOR IMPEDING TRANSCRIPTION OF EXPANDED MICROSATELLITE REPEATS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-05-08 US disclosed
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-04-24 US disclosed
US-12180499-B2 Compositions and methods for impeding transcription of expanded microsatellite repeats UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-12-31 US disclosed
US-20240316204-A1 COCHLEATES MADE WITH SOY PHOSPHATIDYLSERINE MATINAS BIOPHARMA NANOTECHNOLOGIES, INC. 2024-09-26 US disclosed
US-11964019-B2 Cochleates made with soy phosphatidylserine RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-04-23 US disclosed
CN-115043892-B Glycosyl polyether compounds targeting actin 武汉合生科技有限公司 2024-04-12 CN disclosed
US-20230282311-A1 METHOD AND SYSTEM TO IDENTIFY NATURAL PRODUCTS FROM MASS SPECTROMETRY AND GENOMICS DATA UNITED STATES DEPARTMENT OF ENERGY 2023-09-07 US disclosed
EP-4110405-A1 ANTI-CD56 ANTIBODY-DRUG CONJUGATES AND THEIR USE IN THERAPY MCSAF INSIDE ONOCOLOGY (FR) 2023-01-04 EP disclosed
EP-3972652-A1 ANTIBODY-DRUG CONJUGATES AND THEIR USE IN THERAPY Mc SAF (FR) 2022-03-30 EP disclosed
EP-3373993-B1 SI-HPMC-ENCAPSULATED INSULIN-PRODUCING CELLS FOR THE TREATMENT OF TYPE 1 DIABETES ECOLE NAT VETERINAIRE (FR) 2022-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS EPOR, MPL, PRLHR RIPK1 4047/4885
US-20260116986-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS EPOR, STAT5A, JAK2 RIPK1 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.