SCHEMBL29378829

SCHEMBL29378829

CSC1SCC2C(=O)N(C)[C@@H]([C@H](C)C(C)C)C(=O)OC[C@@H](NC(=O)c3cnc4ccccc4n3)C(=O)N[C@@H](C)C(=O)N(C)C1C(=O)N(C)[C@@H]([C@H](C)C(C)C)C(=O)OC[C@@H](NC(=O)c1cnc3ccccc3n1)C(=O)N[C@@H](C)C(=O)N2C

nearest known ligand 0.90

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29885558 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL13464701 0.95 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL29529894 0.95 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL63091 0.95 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL29420869 0.95 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL18477111 0.95 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL13928604 0.95 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL30725384 0.95 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL18506201 0.95 RIPK1 (0.32) RIPK1
SCHEMBL20323949 0.92 RIPK1 (0.31) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
CN-113423430-B Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2024-12-03 CN claimed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-117337196-A Pegylated antibody hydroxyl-containing drug conjugates 深圳康源久远生物技术有限公司 2024-01-02 CN claimed
CN-115666642-A Drug conjugates containing alpha-enolase antibodies and uses thereof 上毅生物科技股份有限公司 2023-01-31 CN claimed
CN-115443134-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2022-12-06 CN claimed
EP-4687444-A1 IMPROVED WAXY DELIVERY FORMS FOR OILY AGRONOMIC ACTIVE INGREDIENTS AND METHOD OF PREPARATION CLEVER BIOSCIENCE S.R.L. (IT) 2026-02-11 EP disclosed
EP-4674476-A1 MAGNETIC FIELD VARIATION THERAPY FOR ENHANCING THERAPEUTIC AND DISINFECTION APPLICATIONS Azyro SA (LU) 2026-01-07 EP disclosed
EP-3802850-B1 DEVICES AND SYSTEMS FOR GASTROINTESTINAL MICROBIOME DETECTION AND MANIPULATION BT BIDCO INC (US) 2025-11-19 EP disclosed
EP-4598583-A2 AMIDE LINKAGES OF SUGAR MOIETIES TO AMINE TERMINATED LEASHES ATTACHED TO CARBOHYDRATE POLYMERS Navidea Biopharmaceuticals, Inc. (US) 2025-08-13 EP disclosed
EP-4569003-A2 CLAUDIN-6 ANTIBODIES AND CONJUGATES THEREOF AND USES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-06-18 EP disclosed
CN-120153254-A Methods for the treatment and diagnosis of bladder cancer 基因泰克公司 2025-06-13 CN disclosed
WO-2022076364-A1 COMPOSITIONS AND METHODS FOR CANCER DIAGNOSIS AOA DX (US) 2022-04-14 WO disclosed
US-20220071559-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT GLAS USA LLC 2022-03-10 US disclosed
US-20220071894-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A CHEMOKINE/CHEMOKINE RECEPTOR INHIBITOR BT BIDCO LLC 2022-03-10 US disclosed
CN-114144169-A Leuprolide acetate compositions and methods of using same for treating breast cancer 托尔玛国际有限公司 2022-03-04 CN disclosed
CN-114040778-A Cell binding molecule-Tubulysin derivative conjugate and preparation method thereof 杭州多禧生物科技有限公司 2022-02-11 CN disclosed
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN disclosed
EP-3551293-B1 RNASE FOR IMPROVED MICROBIAL DETECTION AND ANTIMICROBIAL SUSCEPTIBILITY TESTING MICROBEDX INC (US) 2022-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220071894-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A CHEMOKINE/CHEMOKINE RECEPTOR INHIBITOR ACKR3, CXCR2, CXCR3 RIPK1 1434/4885
US-20220071559-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT TPMT, FABP2, SLC10A2 RIPK1 3212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.