Echinomycin

Echinomycin

SCHEMBL13928604

CSC1SCC2C(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)c3cnc4ccccc4n3)C(=O)N[C@@H](C)C(=O)N(C)C1C(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)c1cnc3ccccc3n1)C(=O)N[C@@H](C)C(=O)N2C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Echinomycin SCHEMBL18506201 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL13464701 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL29529894 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL63091 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL29420869 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL30725384 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL18477111 1.00 RIPK1 (0.32) RIPK1
SCHEMBL20323949 0.96 RIPK1 (0.31) RIPK1
SCHEMBL12556535 0.95 RIPK1 (0.31) RIPK1
SCHEMBL29378829 0.95 RIPK1 (0.32) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105992634-A Selective modification of polymer subunits to improve nanopore-based assays 华盛顿大学商业中心 2016-10-05 CN claimed
CN-102755628-B Antifungal pharmaceutical composition CHINESE ACAD INST MICROBIOLOGY 2013-10-23 CN claimed
CN-102391968-B Streptomyces and its application in echinomycin production CHINESE ACAD INST MICROBIOLOGY 2012-12-19 CN claimed
CN-102791260-A Use of hypoxia inducible factor inhibitors SUNVITA THERAPEUTICS LLC 2012-11-21 CN claimed
CN-102755628-A Antifungal pharmaceutical composition CHINESE ACAD INST MICROBIOLOGY 2012-10-31 CN claimed
CN-102391968-A Streptomyces and its application in echinomycin production CHINESE ACAD INST MICROBIOLOGY 2012-03-28 CN claimed
CN-101795688-A Use of 4- (pyrrolidin-1-yl) quinoline compounds to kill clinically latent microorganisms HELPERBY THERAPEUTICS LTD 2010-08-04 CN claimed
CN-101351203-A Application of pyrroloquinoline compound in killing clinically latent microorganisms HELPERBY THERAPEUTICS LTD (GB) 2009-01-21 CN claimed
CN-101312748-A Antibody-drug conjugates and methods of use MEDAREX INC (US) 2008-11-26 CN claimed
CN-1997402-A Cytotoxic compounds and conjugates MEDAREX INC (US) 2007-07-11 CN claimed
CN-1684642-A Drug release from an antithrombotic multilayer coated stent MEDIPLEX CORP (KR) 2005-10-19 CN claimed
CN-1261803-A Antioxidant enhancement of therapy for hyperproliferative conditions ATHEROGENICS INC (US) 2000-08-02 CN claimed
EP-3137603-B1 A NOVEL AFFINITY MATRIX AND DEVICES FOR ISOLATION AND PURIFICATION OF RNA AND DNA FOR POINT OF CARE MOLECULAR DEVICES ACCUDX CORP (US) 2026-02-18 EP disclosed
US-20250255853-A1 HUMAN THERAPEUTIC AGENTS ANKH LIFE SCIENCES LIMITED (IE) 2025-08-14 US disclosed
US-20240285592-A1 HUMAN THERAPEUTIC AGENTS ANKH LIFE SCIENCES LIMITED (IE) 2024-08-29 US disclosed
WO-2024002385-A1 ECHINOMYCIN ANTIBIOTIC MICELLE, PREPARATION METHOD THEREFOR, AND USE 成都华昊中天药业有限公司 2024-01-04 WO disclosed
CN-1261803-A Antioxidant enhancement of therapy for hyperproliferative conditions ATHEROGENICS INC (US) 2000-08-02 CN disclosed
CN-1238700-A Improvements in or relating to diagnostic and/or therapeutic agents NYCOMED IMAGING AS (NO) 1999-12-15 CN disclosed
CN-1234742-A Improvements in or relating to diagnostic and/or therapeutic agents NYCOMED IMAGING AS (NO) 1999-11-10 CN disclosed
CN-1142828-A Tetrahydrofuran antifungals SCHERING CORP (US) 1997-02-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240285592-A1 HUMAN THERAPEUTIC AGENTS INMT, NLN, MYC RIPK1 807/4885
US-20250255853-A1 HUMAN THERAPEUTIC AGENTS HASPIN, TIPARP, SHARPIN RIPK1 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.