Echinomycin

Echinomycin

SCHEMBL63091

CSC1SCC2C(=O)N(C)C(C(C)C)C(=O)OCC(NC(=O)c3cnc4ccccc4n3)C(=O)NC(C)C(=O)N(C)C1C(=O)N(C)C(C(C)C)C(=O)OCC(NC(=O)c1cnc3ccccc3n1)C(=O)NC(C)C(=O)N2C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Echinomycin SCHEMBL18506201 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL13464701 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL29529894 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL29420869 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL30725384 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL18477111 1.00 RIPK1 (0.32) RIPK1
Echinomycin SCHEMBL13928604 1.00 RIPK1 (0.32) RIPK1
SCHEMBL20323949 0.96 RIPK1 (0.31) RIPK1
SCHEMBL12556535 0.95 RIPK1 (0.31) RIPK1
SCHEMBL29378829 0.95 RIPK1 (0.32) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4024 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739768-A1 PROCESS FOR ESTABLISHING A HUMAN TESTICULAR TISSUE CULTURE SYSTEM Paterna Biosciences Inc. (US) 2026-05-13 EP claimed
EP-4676543-A1 METHODS OF TREATING CANCER USING ANTI-HER2 ANTIBODY-DRUG CONJUGATES AND HER2 KINASE INHIBITORS Seagen Inc. (US) 2026-01-14 EP claimed
WO-2025231217-A1 COMPOSITIONS AND METHODS OF OLIGONUCLEOTIDE HITCHHIKING FOR ENCAPSULATION OF DRUGS IN LIPID NANOPARTICLES UNIVERSITY OF MARYLAND, BALTIMORE (US) 2025-11-06 WO claimed
EP-4615377-A1 DRUG-CONTAINING DEVICES, SUPRACHOROIDAL SPACE IMPLANTS, AND ADAPTERS FOR INJECTION Beijing Sightnovo Medical Technology Co., Ltd (CN) 2025-09-17 EP claimed
CN-120202201-A Inhibitors of ubiquitin-specific protease 1 and uses thereof 深圳晶泰科技有限公司 2025-06-24 CN claimed
US-20250146018-A1 COMPOSITIONS AND METHODS FOR IMPEDING TRANSCRIPTION OF EXPANDED MICROSATELLITE REPEATS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-05-08 US claimed
CN-119868343-A Anti-glioma pharmaceutical composition and application thereof 河北大学附属医院 2025-04-25 CN claimed
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-04-24 US claimed
WO-2025054918-A1 METHODS OF TREATING CANCER USING ANTI-HER2 ANTIBODY-DRUG CONJUGATES AND ANTI-PD-1 ANTIBODIES REMEGEN CO., LTD. (CN) 2025-03-20 WO claimed
WO-2025054916-A1 METHODS OF TREATING CERVICAL CANCER USING ANTI-HER2 ANTIBODY-DRUG CONJUGATES REMEGEN CO., LTD. (CN) 2025-03-20 WO claimed
US-5204238-A Binding an antibiotic on or near the star sequences of the restriction enzyme being used for the specific cleavage of DNA BOEHRINGER MANNHEIM GMBH (DE) 1993-04-20 US claimed
EP-0359347-B1 COVALENTLY-LINKED COMPLEXES AND METHODS FOR ENHANCED CYTOTOXICITY AND IMAGING NEORX CORPORATION (US) 1992-12-23 EP claimed
EP-0449178-A2 Method for the reduction of star activity Roche Diagnostics GmbH (DE) 1991-10-02 EP claimed
US-5024998-A Administering in aqueous solution with cyclodextrin derivative UNIVERSITY OF FLORIDA (US) 1991-06-18 US claimed
US-4983586-A Decreasing precipitation at injection site or in lungs or other organs by combining with hydroxypropyl-beta-cyclodextrin UNIVERSITY OF FLORIDA (US) 1991-01-08 US claimed
EP-0359347-A2 Covalently-linked complexes and methods for enhanced cytotoxicity and imaging NEORX CORPORATION (US) 1990-03-21 EP claimed
EP-0335545-A2 Pharmaceutical formulations for parenteral use UNIVERSITY OF FLORIDA (US) 1989-10-04 EP claimed
EP-0092709-B1 PROCESS FOR PRODUCING L-HYSTIDINE BY FERMENTATION AND MICROORGANISMS THEREFOR KYOWA HAKKO KOGYO CO., LTD. (JP) 1987-07-29 EP claimed
US-4495283-A Process for producing L-histidine by fermentation KYOWA HAKKO KOGYO CO., LTD. (JP) 1985-01-22 US claimed
EP-0092709-A2 Process for producing L-hystidine by fermentation and microorganisms therefor KYOWA HAKKO KOGYO CO., LTD. (JP) 1983-11-02 EP claimed