Thiophanate Methyl

Thiophanate Methyl

SCHEMBL29422247

COC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
LMNA P02545 4/20 1.00
HPGD P15428 3/20 1.00
ALOX15 P16050 1/20 1.00
HSD17B10 Q99714 1/20 1.00
KMT2A Q03164 3/20 0.58
EPHX1 P07099 2/20 0.54
KDM4E B2RXH2 4/20 0.54
ALOX12 P18054 3/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MAPT P10636 4/20 0.53
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophanate Methyl SCHEMBL41622 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDALOX15HSD17B10
Thiophanate Methyl SCHEMBL16537027 0.98 ALDH1A1 (0.96) ALDH1A1LMNAHPGDALOX15HSD17B10
Thiophanate Methyl SCHEMBL28315984 0.98 ALDH1A1 (0.96) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11677871 0.96 ALDH1A1 (0.93) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11676773 0.95 ALDH1A1 (0.90) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11677674 0.93 ALDH1A1 (0.87) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL29376012 0.93 ALDH1A1 (0.87) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11796333 0.93 ALDH1A1 (0.87) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11804708 0.93 ALDH1A1 (0.87) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL11677705 0.93 ALDH1A1 (0.87) ALDH1A1LMNAHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250176549-A1 FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND USES THEREOF ADAMA MAKHTESHIM LTD. (IL) 2025-06-05 US claimed
EP-4486126-A1 FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND USES THEREOF ADAMA MAKHTESHIM LTD. (IL) 2025-01-08 EP claimed
EP-4255175-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE Pioneer Hi-Bred International, Inc. (US) 2023-10-11 EP claimed
WO-2023166485-A1 FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND USES THEREOF ADAMA MAKHTESHIM LTD. (IL) 2023-09-07 WO claimed
US-20230150228-A1 ROLL-UP THERMAL BARRIER RYTEC CORP (US) 2023-05-18 US claimed
EP-2453739-B2 A PROCESS FOR PREPARING AN AQUEOUS SUSPENSION OF AN ORGANIC PESTICIDE COMPOUND BASF SE (DE) 2023-03-01 EP claimed
WO-2022136003-A1 MIXTURES AND COMPOSITIONS COMPRISING FUSARICIDIN A, FUSARICIDIN B AND FUNGICIDES BASF SE (DE) 2022-06-30 WO claimed
WO-2022099169-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-05-12 WO claimed
EP-4735569-A1 ALKYL SULFONIC ACID COMPOSITIONS COMPRISING SOLVENT USEFUL IN DESCALING APPLICATIONS Jelmar LLC (US) 2026-05-06 EP disclosed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
US-20260116872-A1 THIOPHENE BASED APYRASE INHIBITORS TEXAS CROP SCIENCE INC (US) 2026-04-30 US disclosed
US-20260116873-A1 APYRASE INHIBITORS TEXAS CROP SCIENCE INC (US) 2026-04-30 US disclosed
EP-4704819-A1 NANOPARTICLE COMPOSITION FOR OXYGEN DELIVERY Swaza Inc. (US) 2026-03-11 EP disclosed
WO-2026044006-A1 MODIFIED STARCH COMPOUNDS AND USES THEREOF ISP INVESTMENTS LLC (US) 2026-02-26 WO disclosed
WO-2022097598-A1 BENZOXAZINE COMPOUND-CONTAINING COMPOSITION, CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF 本州化学工業株式会社 2022-05-12 WO disclosed
EP-3993626-A1 HERBICIDAL COMPOSITIONS Bayer Aktiengesellschaft (DE) 2022-05-11 EP disclosed
EP-3615540-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2022-04-27 EP disclosed
WO-2022053453-A1 AZOLE CARBOXAMIDE AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2022-03-17 WO disclosed
CN-109553520-B Production process of gold potassium citrate 泰州市欣港电子材料有限公司 2022-02-22 CN disclosed
EP-3952650-A1 FUNGICIDE COMPOSITION FOR CONTROLLING ZYMOSEPTORIA INFECTION IN PLANT UPL Corporation Limited (MU) 2022-02-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116873-A1 APYRASE INHIBITORS APEH, AP3M1, SRR ALDH1A1 2831/4885LMNA 4349/4885HPGD 2400/4885
US-20260116872-A1 THIOPHENE BASED APYRASE INHIBITORS SRR, APEH, OSR1 ALDH1A1 2701/4885LMNA 4794/4885HPGD 3033/4885
US-20250176549-A1 FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND USES THEREOF THRB, OSBP, TPI1 ALDH1A1 2667/4885LMNA 4213/4885HPGD 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.