Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428441 | 0.74 | KMT2A (0.46) | HDAC1TACR1KDM4EALDH1A1NPC1 | |
| SCHEMBL29428436 | 0.72 | HDAC1 (0.40) | HDAC1TACR1KDM4EKMT2A | |
| SCHEMBL28838323 | 0.71 | LMNA (0.44) | HDAC1KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL28838325 | 0.71 | TACR1 (0.51) | HDAC1TACR1MAPT | |
| SCHEMBL8706846 | 0.71 | CES2 (0.53) | HDAC1TACR1KDM4EALDH1A1KMT2A | |
| SCHEMBL7497496 | 0.70 | KMT2A (0.46) | HDAC1KDM4EKMT2A | |
| SCHEMBL17131371 | 0.68 | KMT2A (0.46) | HDAC1TACR1KDM4EALDH1A1KMT2A | |
| SCHEMBL28867967 | 0.67 | KMT2A (0.64) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL28888243 | 0.67 | FOLH1 (0.43) | TDP1GPBAR1HDAC1GAAMAPT | |
| SCHEMBL11785477 | 0.67 | CA12 (0.44) | HDAC1TACR1KDM4ENPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256274-B | Method for preparing N-methyl-N-phenyl-2, 3-dibromo-3-substituted phenylpropionamide compound | 安徽理工大学 | 2022-02-15 | — | — | CN | disclosed |