Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428441 | 0.91 | KMT2A (0.46) | HDAC1KMT2ACA12CA9TACR1 | |
| SCHEMBL28838323 | 0.87 | LMNA (0.44) | HDAC1LMNAKMT2AMEN1ACHE | |
| SCHEMBL28838325 | 0.83 | TACR1 (0.51) | HDAC1TACR1LIPE | |
| SCHEMBL29428448 | 0.82 | ALDH1A1 (0.53) | LMNAKMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL29428440 | 0.76 | TDP1 (0.46) | TRPM8 | |
| SCHEMBL19412474 | 0.75 | ALDH1A1 (0.41) | LMNAKEAP1NFE2L2ACHEPOLB | |
| SCHEMBL11056951 | 0.74 | CES2 (0.48) | LMNAKMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL8706846 | 0.74 | CES2 (0.53) | HDAC1LMNAKMT2ACA12CA9 | |
| SCHEMBL7497496 | 0.73 | KMT2A (0.46) | HDAC1LMNAKMT2ACA12CA9 | |
| SCHEMBL29428437 | 0.72 | TDP1 (0.41) | HDAC1KMT2ATACR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256274-B | Method for preparing N-methyl-N-phenyl-2, 3-dibromo-3-substituted phenylpropionamide compound | 安徽理工大学 | 2022-02-15 | — | — | CN | disclosed |