Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.51 |
| ▸ | POLQ | O75417 | 4/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428441 | 0.85 | KMT2A (0.46) | TACR1HDAC1 | |
| SCHEMBL29428436 | 0.83 | HDAC1 (0.40) | TACR1LIPEHDAC1 | |
| SCHEMBL28838323 | 0.82 | LMNA (0.44) | POLQLIPEHDAC1MAPT | |
| SCHEMBL29428448 | 0.77 | ALDH1A1 (0.53) | MAPT | |
| SCHEMBL28795692 | 0.76 | GSK3B (0.56) | ACP3PDPK1CNR2GSK3BMAPT | |
| SCHEMBL29428440 | 0.72 | TDP1 (0.46) | — | |
| SCHEMBL29428437 | 0.71 | TDP1 (0.41) | TACR1HDAC1MAPT | |
| SCHEMBL8706846 | 0.70 | CES2 (0.53) | TACR1HDAC1 | |
| SCHEMBL7448575 | 0.69 | GSK3B (0.53) | ACP3PDPK1CNR2GSK3B | |
| SCHEMBL2094862 | 0.69 | SMN1; SMN2 (0.51) | TACR1POLQNR1H3MLYCDNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256274-B | Method for preparing N-methyl-N-phenyl-2, 3-dibromo-3-substituted phenylpropionamide compound | 安徽理工大学 | 2022-02-15 | — | — | CN | disclosed |