SCHEMBL29429101

SCHEMBL29429101

Cc1c(C(=O)O)ccc(S(C)(=O)=O)c1C1=NOCC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
GABRA4 P48169 1/20 0.31
GABRE P78334 1/20 0.31
GABRA6 Q16445 1/20 0.31
GABRG1 Q8N1C3 1/20 0.31
GABRG3 Q99928 1/20 0.31
GABRQ Q9UN88 1/20 0.31
BCAT2 O15382 1/20 0.31
EDNRA P25101 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4698411 1.00 GABRP (0.31) GABRPGABRDGABRA1GABRB1GABRG2
Hydrochloric Acid SCHEMBL26633705 0.99 GABRP (0.31) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4703228 0.89
SCHEMBL30608210 0.89
SCHEMBL4699882 0.86 LMNA (0.33) EDNRALMNAKDM4E
SCHEMBL4026666 0.86 LMNA (0.34) BCAT2LMNA
SCHEMBL28530645 0.84 TSHR (0.35) ALDH1A1LMNAKDM4EKMT2A
SCHEMBL13415355 0.81 SMN1; SMN2 (0.35) ALDH1A1LMNA
SCHEMBL701268 0.80 EDNRB (0.30) EDNRA
Topramezone SCHEMBL29566850 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040366-A Preparation method of topramezone intermediate and preparation method of topramezone 合肥星宇化学有限责任公司 2025-05-27 CN claimed
CN-119096982-A Topramezone-containing topramezone Ketone pesticide composition 帕潘纳(北京)科技有限公司 2024-12-10 CN claimed
CN-121202804-A Method for preparing topramezone intermediate 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4- (methylsulfonyl) benzoic acid 苏州开元民生科技股份有限公司 2025-12-26 CN disclosed
CN-121202804-A Method for preparing topramezone intermediate 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4- (methylsulfonyl) benzoic acid 苏州开元民生科技股份有限公司 2025-12-26 CN disclosed
CN-120607495-A Preparation method of 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4- (methylsulfonyl) benzoic acid 北京颖泰嘉和生物科技股份有限公司 2025-09-09 CN disclosed
CN-120607495-A Preparation method of 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4- (methylsulfonyl) benzoic acid 北京颖泰嘉和生物科技股份有限公司 2025-09-09 CN disclosed
CN-120040366-A Preparation method of topramezone intermediate and preparation method of topramezone 合肥星宇化学有限责任公司 2025-05-27 CN disclosed
CN-119096982-A Topramezone-containing topramezone Ketone pesticide composition 帕潘纳(北京)科技有限公司 2024-12-10 CN disclosed
CN-118373783-A Method for preparing topramezone intermediate dihydro-isoxazole compound 帕潘纳(北京)科技有限公司 2024-07-23 CN disclosed
CN-118324705-A Preparation method of isoxazole compound 帕潘纳(北京)科技有限公司 2024-07-12 CN disclosed
CN-118324786-A Preparation method of topramezone intermediate compound 帕潘纳(北京)科技有限公司 2024-07-12 CN disclosed
CN-117986198-A Preparation method of herbicide intermediate 帕潘纳(北京)科技有限公司 2024-05-07 CN disclosed
CN-117986198-A Preparation method of herbicide intermediate 帕潘纳(北京)科技有限公司 2024-05-07 CN disclosed
CN-116947837-A Topramezone intermediate and preparation method thereof 帕潘纳(北京)科技有限公司 2023-10-27 CN disclosed
CN-113862703-B Preparation method of topramezone intermediate 江苏七洲绿色科技研究院有限公司 2023-06-20 CN disclosed
CN-113862703-B Preparation method of topramezone intermediate 江苏七洲绿色科技研究院有限公司 2023-06-20 CN disclosed
CN-114163428-B Preparation method of topramezone 江苏七洲绿色科技研究院有限公司 2022-06-10 CN disclosed
CN-114163428-A Preparation method of topramezone 江苏七洲绿色科技研究院有限公司 2022-03-11 CN disclosed
CN-114057715-A Preparation method of topramezone 安徽宁亿泰科技有限公司 2022-02-18 CN disclosed