Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141778 | 0.83 | ADORA2A (0.64) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7296248 | 0.81 | ADORA2A (0.61) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7295708 | 0.81 | ADORA2A (0.61) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7295604 | 0.80 | ADORA2A (0.59) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31366236 | 0.75 | ADORA2A (0.59) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27621962 | 0.74 | ADORA2B (0.66) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30025357 | 0.72 | ADORA2A (0.66) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5515444 | 0.70 | ADORA2A (0.71) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31065356 | 0.69 | ADORA2A (0.58) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4602969 | 0.68 | ADORA2B (0.73) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |
| EP-3205652-B1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG RAYNOVENT BIOTECH CO LTD (CN) | 2022-03-09 | — | — | EP | disclosed |