Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.59 |
| ▸ | PDE4A | P27815 | 5/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141778 | 0.87 | ADORA2A (0.64) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7296248 | 0.85 | ADORA2A (0.61) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7295708 | 0.85 | ADORA2A (0.61) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7295604 | 0.84 | ADORA2A (0.59) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29429682 | 0.75 | ADORA2A (0.49) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5515444 | 0.75 | ADORA2A (0.71) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL380135 | 0.75 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9329831 | 0.74 | ADORA2A (0.54) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7217322 | 0.74 | ADORA2A (0.97) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4602969 | 0.73 | ADORA2B (0.73) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425508-A1 | COMPOUNDS USEFUL IN PREVENTION AND/OR TREATMENT OF SENESCENT CELL-RELATED PATHOLOGIES AND DISEASES | ISTITUTI CLINICI SCIENTIFICI MAUGERI S.P.A. S.B. (IT) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425508-A1 | COMPOUNDS USEFUL IN PREVENTION AND/OR TREATMENT OF SENESCENT CELL-RELATED PATHOLOGIES AND DISEASES | RB1, CCNH, SIRT7 | ADORA2A 1331/4885PDE4A 4179/4885PDE4B 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.