Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942724 | 0.87 | MAPT (0.39) | MAPTALDH1A1BRS3SERPINE1CYP1A2 | |
| SCHEMBL2941141 | 0.83 | MAPT (0.48) | MAPTALDH1A1HPGDSMN1; SMN2CHRNB2 | |
| SCHEMBL2942020 | 0.83 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2HSD11B1CHRNB2 | |
| SCHEMBL2942154 | 0.82 | FFAR1 (0.33) | MAPT | |
| SCHEMBL2935560 | 0.81 | MAPT (0.42) | MAPTSMN1; SMN2HSD11B1CHRNB2CHRNB4 | |
| SCHEMBL2940852 | 0.80 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2HSD11B1L3MBTL1 | |
| SCHEMBL2934509 | 0.80 | FFAR1 (0.39) | — | |
| SCHEMBL2942230 | 0.77 | HSD11B1 (0.46) | MAPTSERPINE1HSD11B1CYP2C19 | |
| SCHEMBL2942012 | 0.77 | FFAR1 (0.38) | — | |
| SCHEMBL2935646 | 0.76 | FPR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | disclosed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | MAPT 2140/4885ALDH1A1 8/4885HPGD 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.