Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649659 | 0.94 | CYP2D6 (0.46) | — | |
| SCHEMBL30352496 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EPLK1LMNA | |
| SCHEMBL30278608 | 0.82 | TSPO (0.48) | ALDH1A1MAPTTSHRRAB9AMAPK1 | |
| SCHEMBL30065200 | 0.78 | TSPO (0.51) | ALDH1A1MAPTKDM4EMCL1HSD17B10 | |
| SCHEMBL29390820 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4ERAB9APLK1 | |
| SCHEMBL4496895 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MAPTTSHRRAB9AL3MBTL1 | |
| Phenylacetylglycine Dimethylamide SCHEMBL6056919 | 0.75 | ALDH1A1 (0.49) | ALDH1A1TSHRRAB9AL3MBTL1TP53 | |
| SCHEMBL10274491 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4ETSHRRAB9A | |
| SCHEMBL6908413 | 0.73 | LMNA (0.40) | ALDH1A1MAPTHSD17B10L3MBTL1LMNA | |
| SCHEMBL29521154 | 0.72 | L3MBTL1 (0.52) | ALDH1A1MAPTTSHRRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12529705-B2 | Method for detecting the presence and quantity of the LRP8 receptor and of its proteolytic fragments, detection kit and related antibodies | Claudio, Russo (IT) | 2026-01-20 | — | — | US | disclosed |
| EP-3903107-B1 | METHOD FOR DETECTING THE PRESENCE AND QUANTITY OF THE LRP8 RECEPTOR AND OF ITS PROTEOLYTIC FRAGMENTS, DETECTION KIT AND RELATED ANTIBODIES | RUSSO CLAUDIO (IT) | 2025-01-29 | — | — | EP | disclosed |
| US-20220074957-A1 | METHOD FOR DETECTING THE PRESENCE AND QUANTITY OF THE LRP8 RECEPTOR AND OF ITS PROTEOLYTIC FRAGMENTS, DETECTION KIT AND RELATED ANTIBODIES | Russo, Claudio (IT) | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529705-B2 | Method for detecting the presence and quantity of the LRP8 receptor and of its proteolytic fragments, detection kit and related antibodies | BACE1, BACE2, APH1A | ALDH1A1 4335/4885MAPT 783/4885KDM4E 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.