Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947567 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL31339496 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL11540697 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL15344619 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL2943009 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL7796126 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL2946164 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL10820639 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL1080854 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL11883243 | 0.98 | NAAA (0.55) | NAAAEPHX1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586406-B | Preparation method of 3-sulfonyl coumarin compound | 曲阜师范大学 | 2022-03-15 | — | — | CN | claimed |
| CN-108586406-B | Preparation method of 3-sulfonyl coumarin compound | 曲阜师范大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-112321553-A | Method for synthesizing 3-position difluoromethyl substituted coumarin derivative from aryl alkyne acid ester | 天津科技大学 | 2021-02-05 | — | — | CN | disclosed |
| US-20190192524-A1 | Modulators of Caspase-6 | UNIVERSITY OF HAMBURG (DE) | 2019-06-27 | — | — | US | disclosed |
| EP-3129027-A1 | MODULATORS OF CASPASE-6 | University of British Columbia (CA) | 2017-02-15 | — | — | EP | disclosed |
| CN-103833554-B | Method for preparing (2E, 2' E) -acrylate ether compound | 南京工业大学 | 2016-09-14 | — | — | CN | disclosed |
| WO-2016020732-A1 | MODULATORS OF CASPASE-6 | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-02-11 | — | — | WO | disclosed |
| US-9023954-B1 | Side-chain and end-group modified poly-p-phenylene oligomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-05-05 | — | — | US | disclosed |
| US-7727677-B2 | Nonaqueous electrolyte solution and lithium secondary battery using same | UBE INDUSTRIES, LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| EP-1758198-B1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | UBE INDUSTRIES (JP) | 2009-07-08 | — | — | EP | disclosed |
| EP-0389617-B1 | TREATMENT OF RHODIUM CATALYSTS | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0357997-B1 | REACTIVATION OF HYDROFORMYLATION CATALYSTS | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) (US) | 1992-11-25 | — | — | EP | disclosed |
| EP-0389617-A1 | TREATMENT OF RHODIUM CATALYSTS. | UNION CARBIDE CHEM PLASTIC (US) | 1990-10-03 | — | — | EP | disclosed |
| CN-1042483-A | The processing method of rhodium catalyst | UNION CARBIDE CHEM PLASTIC (US) | 1990-05-30 | — | — | CN | disclosed |
| US-4929767-A | PRETREATING AN ORGANIC SOLUTION OF A DEACTIVATED RHODIUM-PHOSPHINE COMPLEX TO IMPROVE RHODIUM EXTRACTABILITY INTO AN AQUEOUS SOLUTION; REUSE | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-05-29 | — | — | US | disclosed |
| WO-1990003841-A1 | TREATMENT OF RHODIUM CATALYSTS | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-04-19 | — | — | WO | disclosed |
| CN-1040746-A | The reactivation of carbonylating catalyst | UNION CARBIDE CHEM PLASTIC (US) | 1990-03-28 | — | — | CN | disclosed |
| EP-0357997-A1 | Reactivation of hydroformylation catalysts | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4870048-A | COLORFAST IMAGE, LIGHT RESISTANCE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| US-4861918-A | RHODIUM-TERITARY ORGANOPHOSPHINE COMPLEX | UNION CARBIDE CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192524-A1 | Modulators of Caspase-6 | CASP6, CASP10, CASP2 | NAAA 804/4885EPHX1 3052/4885CA12 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.