Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.53 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410137 | 1.00 | P2RX7 (0.53) | P2RX7ENPP3ENPP1NOTUMSMN1; SMN2 | |
| SCHEMBL1043059 | 0.83 | P2RX7 (0.57) | P2RX7NOTUMSMN1; SMN2CA2CTSS | |
| SCHEMBL10780671 | 0.81 | P2RX7 (0.34) | P2RX7ENPP3ENPP1HSD11B1CA1 | |
| SCHEMBL11553855 | 0.79 | TSHR (0.33) | P2RX7ENPP3ENPP1CA1CA2 | |
| SCHEMBL22989560 | 0.79 | P2RX7 (0.55) | P2RX7NOTUMSMN1; SMN2CTSSCTSK | |
| Methane SCHEMBL28189445 | 0.77 | P2RX7 (0.53) | P2RX7NOTUMSMN1; SMN2CTSSCTSK | |
| SCHEMBL31226293 | 0.77 | CA2 (0.44) | P2RX7ENPP3ENPP1CA1CA2 | |
| SCHEMBL29764291 | 0.76 | P2RX7 (0.52) | P2RX7NOTUMSMN1; SMN2HSD11B1CTSS | |
| SCHEMBL7191759 | 0.76 | TAS2R14 (0.42) | P2RX7ENPP3ENPP1SMN1; SMN2HSD11B1 | |
| SCHEMBL312929 | 0.76 | P2RX7 (0.52) | P2RX7NOTUMSMN1; SMN2HSD11B1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-114174266-A | Arylsulfonamide derivatives as MGLUR4 negative allosteric modulators | 豪夫迈·罗氏有限公司 | 2022-03-11 | — | — | CN | disclosed |