Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756227 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL19728987 | 0.79 | PIK3CD (0.43) | ALDH1A1POLBKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL1716472 | 0.78 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL120994 | 0.78 | ALDH1A1 (0.56) | ALDH1A1POLBKDM4ESMN1; SMN2PLAU | |
| SCHEMBL30762204 | 0.78 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL29414916 | 0.78 | ALDH1A1 (0.56) | ALDH1A1POLBKDM4ESMN1; SMN2PLAU | |
| SCHEMBL30144074 | 0.77 | AGBL2 (0.47) | ALDH1A1POLBKDM4ESMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3038475 | 0.77 | ALDH1A1 (0.43) | ALDH1A1POLBKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL30062543 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBKDM4ESMN1; SMN2PLAU | |
| SCHEMBL31310688 | 0.77 | PIK3CD (0.50) | ALDH1A1POLBKDM4ESMN1; SMN2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955472-A | 2- (Hetero) aryl substituted fused heterocyclic derivatives as pesticides | 拜耳作物科学股份公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |
| US-20230124087-A1 | KV3 ENHANCERS FOR THE TREATMENT OF COGNITIVE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 2023-04-20 | — | — | US | disclosed |
| EP-3959207-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2022-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230124087-A1 | KV3 ENHANCERS FOR THE TREATMENT OF COGNITIVE DISORDERS | KCNN3, KCNA4, KCNA3 | ALDH1A1 2760/4885POLB 3774/4885KDM4E 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.