Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032050 | 0.88 | FTO (0.74) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL8567853 | 0.87 | FTO (1.00) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL8571494 | 0.84 | FTO (0.71) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL8580142 | 0.84 | FTO (0.88) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL29810840 | 0.84 | FTO (0.92) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL29938908 | 0.82 | FTO (1.00) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL4600340 | 0.82 | FTO (0.79) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL543293 | 0.82 | FTO (1.00) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL8571832 | 0.81 | FTO (0.74) | FTOMEN1MAPTHPGDCYP2C19 | |
| SCHEMBL14213150 | 0.80 | FTO (0.79) | FTOMEN1MAPTHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773236-A | FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS | MOLECULE PROBES, INC. (US) | 1998-06-30 | — | — | US | disclosed |