Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PER2 | O15055 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657194 | 0.88 | GRM5 (0.64) | LMNASMN1; SMN2ALDH1A1L3MBTL1NCOA3 | |
| SCHEMBL30845460 | 0.87 | GRM5 (0.51) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL31667202 | 0.85 | GRM5 (0.52) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL2024893 | 0.85 | KMT2A (0.59) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL29438724 | 0.85 | GRM5 (0.52) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL29500334 | 0.85 | DRD2 (0.54) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL29438621 | 0.84 | GRM5 (0.49) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL7533063 | 0.83 | GRM5 (0.67) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL29438657 | 0.82 | ACHE (0.55) | ALDH1A1DRD2GRM5ACHENPC1 | |
| SCHEMBL3372347 | 0.82 | GRM5 (0.52) | LMNASMN1; SMN2ALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195764-A | Compound as thyroid hormone beta receptor agonist and application thereof | 广东东阳光药业有限公司 | 2022-03-18 | — | — | CN | disclosed |