Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854039 | 1.00 | CCR5 (0.49) | CCR5SLC6A4USP28USP25CYP2A6 | |
| SCHEMBL31717270 | 0.86 | EPHX2 (0.40) | CCR5SLC6A4CYP2A6HRH4MAOA | |
| SCHEMBL2261248 | 0.86 | EPHX2 (0.40) | CCR5SLC6A4CYP2A6HRH4MAOA | |
| Hydrochloric Acid SCHEMBL3713980 | 0.84 | EPHX2 (0.40) | CCR5SLC6A4CYP2A6HRH4MAOA | |
| Hydrochloric Acid SCHEMBL31717834 | 0.84 | EPHX2 (0.40) | CCR5SLC6A4CYP2A6HRH4MAOA | |
| SCHEMBL3853386 | 0.84 | SLC6A4 (0.40) | CCR5SLC6A4USP28USP25TDP1 | |
| SCHEMBL3372357 | 0.82 | PTGDR2 (0.53) | CCR5SLC6A4USP28USP25TDP1 | |
| SCHEMBL30468149 | 0.81 | SLC6A4 (0.38) | SLC6A4USP28USP25TDP1ALDH1A1 | |
| SCHEMBL18543262 | 0.80 | MPO (0.44) | SLC6A4EPHX2 | |
| SCHEMBL20303640 | 0.79 | USP28 (0.44) | SLC6A4USP28USP25MAPK1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152959-A | N- (3- (aminomethyl) -phenyl) -5- (4-phenyl) -5- (trifluoromethyl) -4, 5-dihydroisoxazol-3-amine derivatives and similar compounds as pesticides | 巴斯夫欧洲公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |