Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674674 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2C9MAPTMEN1 | |
| SCHEMBL8778085 | 0.86 | TNF (0.44) | ALDH1A1CYP1A2CYP2C9MAPTMEN1 | |
| SCHEMBL3678891 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9MAPTMEN1 | |
| SCHEMBL5865650 | 0.85 | PIN1 (0.51) | ALDH1A1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL28278868 | 0.85 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C9MAPTMEN1 | |
| SCHEMBL2957041 | 0.85 | TDP1 (0.57) | ALDH1A1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL16142399 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9MAPTMEN1 | |
| SCHEMBL1537373 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C9MAPTMEN1 | |
| SCHEMBL29256401 | 0.82 | KMT2A (0.42) | ALDH1A1CYP1A2CYP2C9MAPTMEN1 | |
| SCHEMBL12091766 | 0.82 | CYP2D6 (0.49) | ALDH1A1CYP1A2CYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| EP-3976597-B1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-28 | — | — | EP | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |