SCHEMBL2957041

SCHEMBL2957041

CCC(=O)ON1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.57
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 5/20 0.54
HPGD P15428 5/20 0.54
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
HSD17B10 Q99714 2/20 0.54
CYP1B1 Q16678 1/20 0.54
MAPT P10636 2/20 0.50
CYP1A2 P05177 1/20 0.50
AKR1B1 P15121 1/20 0.50
ALOX15 P16050 1/20 0.50
ERCC1 P07992 1/20 0.50
FEN1 P39748 1/20 0.50
ERCC4 Q92889 1/20 0.50
POLB P06746 2/20 0.49
HEXA P06865 3/20 0.48
HEXB P07686 3/20 0.48
CASP1 P29466 1/20 0.46
MPI P34949 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24169113 0.88 TDP1 (0.58) TDP1ALDH1A1KDM4EHPGDMEN1
SCHEMBL25760753 0.85 TDP1 (0.63) TDP1ALDH1A1KDM4EHPGDMEN1
SCHEMBL5865650 0.85 PIN1 (0.51) TDP1ALDH1A1KDM4EHPGDMEN1
SCHEMBL3674674 0.85 ALDH1A1 (0.49) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL29439840 0.85 ALDH1A1 (0.49) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL2957046 0.84 TDP1 (0.62) TDP1ALDH1A1KDM4EHPGDMEN1
SCHEMBL4311303 0.83 TDP1 (0.60) TDP1ALDH1A1KDM4EHPGDMEN1
SCHEMBL8778085 0.83 TNF (0.44) TDP1ALDH1A1KDM4EHPGDMEN1
SCHEMBL2959934 0.82 ALDH1A1 (0.64) TDP1ALDH1A1KDM4EHPGDMEN1
SCHEMBL13898509 0.79 ALDH1A1 (0.56) TDP1ALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433527-B1 CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS DAICEL CHEM (JP) 2013-11-06 EP disclosed
US-7759515-B2 Catalyst comprising N-substituted cyclic imide compound and process for producing organic compounds using the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-07-20 US disclosed
US-20060229196-A1 Catalyst comprising n-substituted cyclic imide compound and process for producing organic compounds using the catalyst ISHII YASUTAKA 2006-10-12 US disclosed
US-7084090-B2 Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-01 US disclosed
CN-1264607-C Catalysts comprised of N-substituted cyclic imides and processes for preparing organic compounds with catalysts DAICEL CHEM (JP) 2006-07-19 CN disclosed
EP-1433527-A1 CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS Daicel Chemical Industries, Ltd. (JP) 2004-06-30 EP disclosed
US-20040053778-A1 Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-03-18 US disclosed
CN-1476352-A Catalysts comprised of N-substituted cyclic imides and processes for preparing organic compounds with catalysts ����贻�ѧ��ҵ��ʽ���� 2004-02-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229196-A1 Catalyst comprising n-substituted cyclic imide compound and process for producing organic compounds using the catalyst NOS2, NOS1, NOS3 TDP1 3824/4885ALDH1A1 1553/4885KDM4E 3183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.