SCHEMBL8778085

SCHEMBL8778085

CCC(=O)ON1C(=O)c2cc3ccccc3cc2C1=O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.44
ALDH1A1 P00352 4/20 0.40
CYP1A2 P05177 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
PDGFRB P09619 1/20 0.37
PDGFRA P16234 1/20 0.37
ELANE P08246 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
CES1 P23141 1/20 0.36
CYP2C9 P11712 1/20 0.36
MMP1 P03956 1/20 0.36
MMP9 P14780 1/20 0.36
MAPT P10636 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29439840 0.86 ALDH1A1 (0.49) ALDH1A1CYP1A2MEN1KMT2ASMN1; SMN2
SCHEMBL3674674 0.86 ALDH1A1 (0.49) ALDH1A1CYP1A2MEN1KMT2ASMN1; SMN2
SCHEMBL2957041 0.83 TDP1 (0.57) ALDH1A1CYP1A2MEN1KMT2ASMN1; SMN2
SCHEMBL5865650 0.80 PIN1 (0.51) ALDH1A1CYP1A2MEN1KMT2ASMN1; SMN2
SCHEMBL13327133 0.77 ALDH1A1 (0.37) TNFALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL12091766 0.74 CYP2D6 (0.49) ALDH1A1CYP1A2MEN1KMT2ASMN1; SMN2
SCHEMBL3678891 0.73 ALDH1A1 (0.50) ALDH1A1CYP1A2MEN1KMT2AKDM4E
SCHEMBL13495401 0.73 MAOA (0.43) TNFALDH1A1CYP1A2MEN1KMT2A
SCHEMBL28278868 0.73 ALDH1A1 (0.43) ALDH1A1CYP1A2MEN1KMT2ASMN1; SMN2
SCHEMBL27703399 0.73 CES1 (0.56) ALDH1A1MEN1KMT2ACES1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576622-B1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK CO (US) 1997-11-05 EP disclosed
EP-0576622-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
WO-1992017821-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1992-10-15 WO disclosed
US-5141839-A LITHOGRAPHIC PRINTING PLATES HAVING A RADIATION-SENSITIVE LAYER COMPRISING A PHOTOCROSSLINKABLE POLYMER, A LEUCO DYE, A PHOTOOXIDANT AND A HETEROAROMATIC AMINE N-OXIDE EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed
US-5141842-A Negative working lithography printing plates EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed