Dusquetide

Dusquetide

SCHEMBL29440126

CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NTSR1 P30989 12/20 0.55
▸ NTSR2 O95665 11/20 0.55
▸ SORT1 Q99523 6/20 0.55
▸ AGTR1 P30556 3/20 0.52
▸ AGTR2 P50052 2/20 0.52
▸ NPY1R P25929 1/20 0.48
▸ NPY2R P49146 1/20 0.48
▸ NPY4R P50391 1/20 0.48
▸ NPY5R Q15761 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dusquetide SCHEMBL16677021 0.86 NTSR1 (0.45) NTSR1NTSR2SORT1
Dusquetide SCHEMBL16671001 0.86 NTSR1 (0.45) NTSR1NTSR2SORT1
SCHEMBL29551878 0.82 OPRD1 (0.56) NTSR1NTSR2SORT1AGTR1NPY1R
SCHEMBL30157099 0.77 XIAP (0.60) —
SCHEMBL30716931 0.76 NTSR1 (0.55) NTSR1NTSR2SORT1AGTR1AGTR2
SCHEMBL29873831 0.75 XIAP (0.51) NTSR1NTSR2SORT1AGTR1AGTR2
SCHEMBL29976151 0.75 CALCRL (0.44) NTSR1NTSR2SORT1
SCHEMBL28363525 0.74 CAPN1 (0.54) NTSR1NTSR2
SCHEMBL30572412 0.74 CAPN1 (0.54) NTSR1NTSR2
SCHEMBL29497357 0.73 XIAP (0.71) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024104197-A1 PEPTIDE HYDROGEL, PREPARATION METHOD THEREFOR AND USE THEREOF IN TREATMENT 中国科学院过程工程研究所 2024-05-23 — — WO disclosed
US-20240016882-A1 AUTOPHAGY-INHIBITING PEPTIDE AND ORGANIC ACID SALT THEREOF ADDRESSING ISSUES OF VASCULAR PERMEABILITY BIOTEMPT B.V. (NL) 2024-01-18 — — US disclosed
EP-3044229-B1 PEPTIDES FOR USE IN THE TREATMENT OF ORAL MUCOSITIS SOLIGENIX INC (US) 2023-10-04 — — EP disclosed
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIV STRASBOURG (FR) 2023-06-08 — — US disclosed
CN-116139248-A Peptide hydrogel, preparation method thereof and application thereof in treatment 中国科学院过程工程研究所 2023-05-23 — — CN disclosed
US-11311598-B2 Peptides and analogs for use in the treatment of oral mucositis SOLIGENIX, INC. (US) 2022-04-26 — — US disclosed
WO-2022069576-A1 AUTOPHAGY-INHIBITING PEPTIDE AND ORGANIC ACID SALT THEREOF ADDRESSING ISSUES OF VASCULAR PERMEABILITY BIOTEMPT B.V. (NL) 2022-04-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11311598-B2 Peptides and analogs for use in the treatment of oral mucositis IFNAR1, DCLRE1A, VIP NTSR1 399/4885NTSR2 816/4885SORT1 4644/4885
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS GPR119, GLP1R, GIPR NTSR1 35/4885NTSR2 27/4885SORT1 2483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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