Dusquetide

Dusquetide

SCHEMBL16671001

CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NTSR1 P30989 16/20 0.45
▸ NTSR2 O95665 15/20 0.45
▸ SORT1 Q99523 14/20 0.45
▸ XIAP P98170 1/20 0.44
▸ PLK1 P53350 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dusquetide SCHEMBL16677021 1.00 NTSR1 (0.45) NTSR1NTSR2SORT1XIAPPLK1
Dusquetide SCHEMBL29440126 0.86 NTSR1 (0.55) NTSR1NTSR2SORT1
SCHEMBL32679557 0.86 NTSR2 (0.45) NTSR1NTSR2SORT1XIAP
SCHEMBL24452714 0.85 KMT2A (0.44) NTSR1NTSR2SORT1XIAP
SCHEMBL30798320 0.84 EPHA2 (0.43) NTSR1NTSR2SORT1XIAPPLK1
SCHEMBL31256957 0.83 XIAP (0.52) NTSR1NTSR2SORT1XIAP
SCHEMBL31461942 0.82 NTSR1 (0.50) NTSR1NTSR2SORT1PLK1
SCHEMBL31427004 0.82 NRP1 (0.44) NTSR1NTSR2SORT1XIAP
SCHEMBL29410233 0.81 EPHA2 (0.47) NTSR1NTSR2SORT1
SCHEMBL31461877 0.81 NTSR1 (0.43) NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240415798-A1 COMPOSITIONS AND METHODS FOR TREATING MUCOSITIS ENZYCHEM LIFESCIENCES CORP (KR) 2024-12-19 — — US claimed
EP-4419096-A1 COMPOSITIONS AND METHODS FOR TREATING MUCOSITIS Enzychem Lifesciences Corporation (KR) 2024-08-28 — — EP claimed
US-11903992-B2 Composition comprising lidocaine, l-carnosine and dexpanthenol CELLIX BIO PRIVATE LIMITED (IN) 2024-02-20 — — US claimed
CN-116687784-A Beauty soluble microneedle, preparation method and application 安徽医科大学 2023-09-05 — — CN claimed
WO-2023067501-A1 COMPOSITIONS AND METHODS FOR TREATING MUCOSITIS ENZYCHEM LIFESCIENCES CORPORATION (KR) 2023-04-27 — — WO claimed
WO-2022157587-A1 A COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL CELLIX BIO PRIVATE LIMITED (IN) 2022-07-28 — — WO claimed
US-20220233629-A1 COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL CELLIX BIO PRIVATE LIMITED (IN) 2022-07-28 — — US claimed
US-20220023419-A1 INHIBITING INFLAMMATION FRED HUTCHINSON CANCER CENTER 2022-01-27 — — US claimed
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2026-05-14 — — US disclosed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-12503436-B2 Compounds and compositions for treating conditions associated with STING activity NOVARTIS PHARMA AG (CH) 2025-12-23 — — US disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
US-20220023022-A1 METHOD AND DEVICE FOR THE ENHANCEMENT OF TOPICAL TREATMENTS FOR ORAL MUCOSITIS AND OTHER ORAL CONDITIONS E2BIO LIFE SCIENCES, LLC (US) 2022-01-27 — — US disclosed
US-20220023419-A1 INHIBITING INFLAMMATION FRED HUTCHINSON CANCER CENTER 2022-01-27 — — US disclosed
US-11229578-B2 Method and device for the enhancement of topical treatments for oral mucositis and other oral conditions E2BIO LIFE SCIENCES, LLC (US) 2022-01-25 — — US disclosed
US-20150148304-A1 Novel Peptides and Analogs for Use in the Treatment of Macrophage Activation Syndrome SOLIGENIX INC (US) 2015-05-28 — — US disclosed
WO-2015061682-A2 NOVEL PEPTIDES AND ANALOGS FOR USE IN THE TREATMENT OF MACROPHAGE ACTIVATION SYNDROME SOLIGENIX, INC. (US) 2015-04-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS NTSR1 59/4885NTSR2 54/4885SORT1 4244/4885
US-20240415798-A1 COMPOSITIONS AND METHODS FOR TREATING MUCOSITIS IL18, MMP8, ELANE NTSR1 3811/4885NTSR2 3966/4885SORT1 4222/4885
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, IRF3, CGAS NTSR1 1893/4885NTSR2 2640/4885SORT1 4850/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 NTSR1 60/4885NTSR2 114/4885SORT1 3626/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 NTSR1 113/4885NTSR2 315/4885SORT1 4138/4885
US-12503436-B2 Compounds and compositions for treating conditions associated with STING activity STING1, CGAS, IRF3 NTSR1 3913/4885NTSR2 4065/4885SORT1 4822/4885
US-11903992-B2 Composition comprising lidocaine, l-carnosine and dexpanthenol VNN1, LPL, HMGB1 NTSR1 4139/4885NTSR2 4408/4885SORT1 4872/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT NTSR1 86/4885NTSR2 199/4885SORT1 4148/4885
US-20150148304-A1 Novel Peptides and Analogs for Use in the Treatment of Macrophage Activation Syndrome VIP, IFNAR1, MYD88 NTSR1 753/4885NTSR2 1609/4885SORT1 4540/4885
US-20220233629-A1 COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL VNN1, LPL, HMGB1 NTSR1 4139/4885NTSR2 4408/4885SORT1 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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