SCHEMBL29440830

SCHEMBL29440830

[2H]OC(=O)c1cccc(O)c1N

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP7 P55210 2/20 0.74
G6PD P11413 1/20 0.74
CASP6 P55212 1/20 0.74
KDM4E B2RXH2 8/20 0.51
HIF1A Q16665 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
ALDH1A1 P00352 7/20 0.43
HPGD P15428 5/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HMGB1 P09429 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
MMP2 P08253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21114369 0.85 CASP7 (1.00) CASP7G6PDCASP6KDM4EHIF1A
SCHEMBL30477210 0.85 CASP7 (1.00) CASP7G6PDCASP6KDM4EHIF1A
SCHEMBL29430959 0.85 CASP7 (1.00) CASP7G6PDCASP6KDM4EHIF1A
SCHEMBL88229 0.85 CASP7 (1.00) CASP7G6PDCASP6KDM4EHIF1A
Bromide SCHEMBL1026209 0.83 CASP7 (0.96) CASP7G6PDCASP6KDM4EHIF1A
Hydrochloric Acid SCHEMBL8584593 0.83 CASP7 (0.96) CASP7G6PDCASP6KDM4EHIF1A
Salicylic Acid SCHEMBL29352029 0.79 KDM4E (0.70) CASP7G6PDCASP6KDM4EHIF1A
SCHEMBL717462 0.79 G6PD (0.72) CASP7G6PDCASP6KDM4EHIF1A
Anthranilic Acid SCHEMBL28496828 0.77 G6PD (0.81) CASP7G6PDCASP6KDM4EHIF1A
SCHEMBL2020740 0.77 G6PD (0.69) CASP7G6PDCASP6KDM4EHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117070584-A Synthesis method of nicotinamide adenine dinucleotide compound 中国科学院微生物研究所 2023-11-17 CN disclosed
CN-114137098-A Method for detecting tryptophan in human plasma and metabolite thereof 中科新生命(浙江)生物科技有限公司 2022-03-04 CN disclosed