SCHEMBL29441278

SCHEMBL29441278

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@@H](O)[C@@]4(O)C[C@@H](OC(=O)CCC(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.73

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPC1L1 Q9UHC9 10/20 0.73
▸ MEN1 O00255 1/20 0.69
▸ USP2 O75604 1/20 0.69
▸ LMNA P02545 1/20 0.69
▸ TP53 P04637 1/20 0.69
▸ KMT2A Q03164 1/20 0.69
▸ NPC1 O15118 1/20 0.66
▸ CDC25A P30304 2/20 0.53
▸ POLA1 P09884 1/20 0.53
▸ FNTA P49354 2/20 0.50
▸ FNTB P49356 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397341 0.90 NPC1L1 (0.59) NPC1L1MEN1USP2LMNATP53
SCHEMBL6391409 0.84 NPC1L1 (0.73) NPC1L1MEN1USP2LMNATP53
SCHEMBL6390397 0.84 NPC1L1 (0.73) NPC1L1MEN1USP2LMNATP53
SCHEMBL6387174 0.84 NPC1L1 (0.73) NPC1L1MEN1USP2LMNATP53
SCHEMBL7124642 0.84 NPC1L1 (0.73) NPC1L1MEN1USP2LMNATP53
SCHEMBL25337296 0.84 NPC1L1 (0.64) NPC1L1MEN1USP2LMNATP53
SCHEMBL29354605 0.83 NPC1L1 (0.72) NPC1L1MEN1USP2LMNATP53
SCHEMBL23452797 0.83 NPC1L1 (0.67) NPC1L1MEN1USP2LMNATP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL25277367 0.82 NPC1L1 (1.00) NPC1L1MEN1USP2LMNATP53
Cholestan-3Beta,5Alpha,6Beta-Triol SCHEMBL14490136 0.82 NPC1L1 (1.00) NPC1L1MEN1USP2LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665733-A1 AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 Bristol-Myers Squibb Company (US) 2025-12-24 — — EP claimed
WO-2024173323-A1 AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 BRISTOL-MYERS SQUIBB COMPANY (US) 2024-08-22 — — WO claimed
CN-117894369-A Screening method of plant environment adaptability candidate genes based on selective elimination SNP guidance 华南农业大学 2024-04-16 — — CN claimed
CN-113591579-B Significance target detection method based on attention mechanism convolutional neural network 河北师范大学 2024-02-13 — — CN claimed
CN-115768892-A Herpes zoster vaccine comprising a TLR9 agonist 戴纳瓦克斯技术公司 2023-03-07 — — CN claimed
CN-115627270-A Label-free ratio type malachite green luminescence aptamer biosensor 中国农业大学 2023-01-20 — — CN claimed
CN-115040532-A Treatment of cancer using TLR9 agonists and checkpoint inhibitors 伊黛拉制药有限公司 2022-09-13 — — CN claimed
EP-4003955-A1 INHIBITORS OF HUMAN ATGL Karl-Franzens-Universität Graz (AT) 2022-06-01 — — EP claimed
CN-114444689-A Transformer temperature detection and analysis method 国网山东省电力公司德州供电公司 2022-05-06 — — CN claimed
CN-114089046-A ZPW-2000 series track circuit compensation capacitance parameter estimation method and device 四川高新轨道交通产业技术研究院 2022-02-25 — — CN claimed
CN-116874755-B Composite titanium catalyst and preparation method and application thereof 浙江糖能科技有限公司 2026-05-22 — — CN disclosed
US-20260135023-A1 HIGH-COERCIVITY AND HIGH-REMANENCE NdFeB MAGNET AND PREPARATION METHOD BEIJING ZHONG KE SAN HUAN HI TECH CO LTD (CN) 2026-05-14 — — US disclosed
US-20260094743-A1 NdFeB MAGNET NINGBO KONIT IND INC (CN) 2026-04-02 — — US disclosed
US-20260083856-A1 THIAZOLIDINE LINKERS FOR PROTEIN-DRUG CONJUGATES AND USES THEREOF SCHERER TECHNOLOGIES LLC R P (US) 2026-03-26 — — US disclosed
US-12571026-B2 Probes for improved melt discrimination and multiplexing in nucleic acid assays LUMINEX CORPORATION (US) 2026-03-10 — — US disclosed
CN-114349368-A Chemically strengthened glass and glass for chemical strengthening AGC株式会社 2022-04-15 — — CN disclosed
CN-114315133-A Chemically strengthened glass and glass for chemical strengthening AGC株式会社 2022-04-12 — — CN disclosed
CN-110892296-B Composition for forming infrared-transmitting film, method for forming infrared-transmitting film, protective plate for display device, and display device JSR株式会社 2022-03-22 — — CN disclosed
EP-3967771-A1 PROBES FOR IMPROVED MELT DISCRIMINATION AND MULTIPLEXING IN NUCLEIC ACID ASSAYS Luminex Corporation (US) 2022-03-16 — — EP disclosed
US-11261481-B2 Probes for improved melt discrimination and multiplexing in nucleic acid assays LUMINEX CORPORATION (US) 2022-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260094743-A1 NdFeB MAGNET TPR, NDC1, TCP1 NPC1L1 1596/4885MEN1 468/4885USP2 3527/4885
US-20260083856-A1 THIAZOLIDINE LINKERS FOR PROTEIN-DRUG CONJUGATES AND USES THEREOF BRWD1, TMIGD3, TXNL1 NPC1L1 987/4885MEN1 2536/4885USP2 2115/4885
US-20260135023-A1 HIGH-COERCIVITY AND HIGH-REMANENCE NdFeB MAGNET AND PREPARATION METHOD LBR, HBB, MYB NPC1L1 1245/4885MEN1 1057/4885USP2 2979/4885
US-12571026-B2 Probes for improved melt discrimination and multiplexing in nucleic acid assays CPSF6, CPSF1, NUDT21 NPC1L1 4664/4885MEN1 1537/4885USP2 2788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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