SCHEMBL2944230

SCHEMBL2944230

CCCCCCCC(C(=O)OC)C(=O)OC

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.66
CA2 P00918 2/20 0.53
CA1 P00915 1/20 0.53
ABCB1 P08183 1/20 0.50
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.49
GPR84 Q9NQS5 7/20 0.47
FFAR1 O14842 1/20 0.47
EPHX1 P07099 2/20 0.45
MAPT P10636 1/20 0.45
LCK P06239 1/20 0.45
PPARD Q03181 1/20 0.45
ZDHHC20 Q5W0Z9 1/20 0.45
ZDHHC2 Q9UIJ5 1/20 0.45
BIRC2 Q13490 1/20 0.44
FAAH O00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9781800 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL8991586 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL2298322 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL8816706 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL8584856 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL486955 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL16832270 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL7543085 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL2293185 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2
SCHEMBL11160681 1.00 ZDHHC7 (0.66) ZDHHC7CA2CA1ABCB1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524975-B2 Amphiphilic compound having dendronic hydrophobic group and application thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2022-12-13 US disclosed
US-20200247836-A1 NOVEL AMPHIPHILIC COMPOUND HAVING DENDRONIC HYDROPHOBIC GROUP AND APPLICATION THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2020-08-06 US disclosed
US-20160039879-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF S&T GLOBAL INC. (US) 2016-02-11 US disclosed
EP-2137179-B1 PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS MERCK SHARP & DOHME (US) 2015-09-02 EP disclosed
EP-2586778-A2 Pyridazinone derivatives useful as glucan synthase inhibitors Merck Sharp & Dohme Corp. (US) 2013-05-01 EP disclosed
US-8232274-B2 Pyridazinone derivatives useful as glucan synthase inhibitors ALBANY MOLECULAR RESEARCH, INC. (US) 2012-07-31 US disclosed
US-8232274-B2 Pyridazinone derivatives useful as glucan synthase inhibitors ALBANY MOLECULAR RESEARCH, INC. (US) 2012-07-31 US disclosed
US-7749399-B2 Method for producing flexographic printing plates using direct laser engraving XSYS PRINT SOLUTIONS DEUTSCHLAND GMBH (DE) 2010-07-06 US disclosed
US-20090170861-A1 Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. 2009-07-02 US disclosed
US-20090170861-A1 Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. 2009-07-02 US disclosed
EP-0306919-B1 LIQUID CRYSTALLINE COMPOUNDS AND PROCESS FOR PRODUCTION THEREOF DAISO CO., LTD. (JP) 1993-02-17 EP disclosed
CN-1052667-A OXAZOLE DERIVATIVES BRISTOL MYERS SQUIBB CO (US) 1991-07-03 CN disclosed
US-5026506-A High capacity displays SHARP KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
EP-0410447-A2 Liquid crystalline compounds, liquid crystal compositions containing the same and use thereof DAISO CO., LTD. (JP) 1991-01-30 EP disclosed
US-4973425-A ELECTROOPTICS DAISO CO., LTD. (JP) 1990-11-27 US disclosed
US-4909957-A Containing lactone ring structure DAISO CO., LTD. (JP) 1990-03-20 US disclosed
EP-0355830-A2 Liquid crystal composition and use thereof DAISO CO., LTD. (JP) 1990-02-28 EP disclosed
EP-0306919-A2 Liquid crystalline compounds and process for production thereof DAISO CO., LTD. (JP) 1989-03-15 EP disclosed
US-4335012-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1982-06-15 US disclosed
US-4322354-A 5-Substituted-2-(4-cyanophenyl)-1,3,-dioxanes TIMEX CORPORATION (US) 1982-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170861-A1 Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors MAN2A1, GYS2, MANBA ZDHHC7 4416/4885CA2 3206/4885CA1 4563/4885
US-20200247836-A1 NOVEL AMPHIPHILIC COMPOUND HAVING DENDRONIC HYDROPHOBIC GROUP AND APPLICATION THEREOF CETP, MDN1, TGOLN2 ZDHHC7 482/4885CA2 3072/4885CA1 2828/4885
US-11524975-B2 Amphiphilic compound having dendronic hydrophobic group and application thereof CETP, TGOLN2, MDN1 ZDHHC7 424/4885CA2 2728/4885CA1 2525/4885
US-20160039879-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF FKBP1B, MALT1, FKBP5 ZDHHC7 425/4885CA2 1053/4885CA1 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.