Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 4/20 | 0.50 |
| ▸ | CCKAR | P32238 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602182 | 1.00 | OPRK1 (0.51) | OPRK1OPRM1OPRD1BACE1CCKAR | |
| SCHEMBL30397713 | 0.92 | OPRM1 (0.53) | OPRK1OPRM1OPRD1BACE1CTSD | |
| SCHEMBL29856025 | 0.90 | TFPI (0.56) | OPRK1OPRM1OPRD1CCKBR | |
| SCHEMBL29569118 | 0.89 | OPRK1 (0.54) | OPRK1OPRM1OPRD1BACE1CTSD | |
| SCHEMBL30420308 | 0.89 | OPRD1 (0.52) | OPRK1OPRM1OPRD1BACE1CCKBR | |
| SCHEMBL30733256 | 0.87 | OPRK1 (0.58) | OPRK1OPRM1BACE1CTSDBACE2 | |
| SCHEMBL29789569 | 0.86 | OPRK1 (0.54) | OPRK1OPRM1OPRD1 | |
| SCHEMBL30435360 | 0.85 | OPRK1 (0.54) | OPRK1OPRM1OPRD1BACE1CTSD | |
| SCHEMBL31211792 | 0.84 | MMP2 (0.48) | BACE1CCKARCCKBR | |
| SCHEMBL30397813 | 0.84 | BACE1 (0.60) | OPRK1BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344642-B2 | Variant survivin vaccine for treatment of myeloma | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2025-07-01 | — | — | US | disclosed |
| CN-110418648-B | mRNA cancer vaccine for encoding fusion of human GM-CSF and multiple tandem epitopes | 丁恩雨 | 2023-09-08 | — | — | CN | disclosed |
| US-20220106370-A1 | VARIANT SURVIVIN VACCINE FOR TREATMENT OF CANCER | H LEE MOFFITT CANCER CT & RES (US) | 2022-04-07 | — | — | US | disclosed |