Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 4/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397109 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL29443526 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL678359 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL1223251 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL1397102 | 0.91 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL679154 | 0.90 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL1918698 | 0.90 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| Potassium SCHEMBL679156 | 0.90 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL16076589 | 0.89 | DHPS (0.38) | ALDH1A1KDM4EHSD17B10DHPSKMO | |
| SCHEMBL30151443 | 0.89 | KDM4E (0.39) | ALDH1A1KDM4EHSD17B10DHPSMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763447-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2017-09-19 | — | — | US | claimed |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CORTEVA AGRISCIENCE LLC | 2016-11-03 | — | — | US | claimed |
| US-9408387-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2016-08-09 | — | — | US | claimed |
| EP-2493292-B1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2016-05-18 | — | — | EP | claimed |
| US-8609592-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | claimed |
| CN-102686106-A | Reducing injury to cereal crops from 6-amino-2- (substituted phenyl) -5-substituted-4-pyrimidinecarboxylic herbicides | DOW AGROSCIENCES LLC | 2012-09-19 | — | — | CN | claimed |
| EP-2493292-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | Dow AgroSciences LLC (US) | 2012-09-05 | — | — | EP | claimed |
| WO-2011059718-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2011-05-19 | — | — | WO | claimed |
| US-20110105325-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC | 2011-05-05 | — | — | US | claimed |
| US-9763447-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CORTEVA AGRISCIENCE LLC | 2016-11-03 | — | — | US | disclosed |
| US-9408387-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2016-08-09 | — | — | US | disclosed |
| EP-2493292-B1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2016-05-18 | — | — | EP | disclosed |
| US-8609592-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-7642220-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2010-01-05 | — | — | US | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105325-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CASP6, CASP2, DHFR | ALDH1A1 2033/4885KDM4E 1445/4885HSD17B10 2615/4885 |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CASP6, CASP2, DHFR | ALDH1A1 2033/4885KDM4E 1445/4885HSD17B10 2615/4885 |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, AADAC | ALDH1A1 504/4885KDM4E 381/4885HSD17B10 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.