Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | GAA | P10253 | 6/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183066 | 0.96 | MAPT (0.69) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL32669023 | 0.87 | MAPT (0.58) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL1921447 | 0.85 | RAPGEF4 (0.50) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL2931765 | 0.85 | MAPT (0.74) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL4945848 | 0.85 | MAPT (0.65) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL2602405 | 0.82 | MAPT (1.00) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL14068594 | 0.80 | MAPT (0.59) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL28005209 | 0.79 | MAPT (0.58) | MAPTGAATDP1KDM4EHPGD | |
| SCHEMBL22434027 | 0.79 | RAPGEF4 (0.50) | MAPTGAATDP1TP53ALDH1A1 | |
| SCHEMBL28187383 | 0.79 | NPSR1 (0.57) | MAPTGAATDP1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759295-B2 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2010-07-20 | — | — | US | claimed |