Sugi Predict

Sugi Predict / Compounds / SCHEMBL1921447

SCHEMBL1921447

SCHEMBL1921447

Cc1cc(C)cc(Nc2ccccc2Nc2cc(C)cc(C)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAPGEF4 Q8WZA2 1/20 0.50
▸ NPC1 O15118 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ MAPT P10636 6/20 0.47
▸ GAA P10253 2/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.46
▸ TAS2R14 Q9NYV8 1/20 0.46
▸ TP53 P04637 3/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ GLA P06280 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ RCE1 Q9Y256 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28187383 0.93 NPSR1 (0.57) RAPGEF4NPC1RAB9AMEN1KMT2A
SCHEMBL22434027 0.89 RAPGEF4 (0.50) RAPGEF4NPC1RAB9AMEN1KMT2A
SCHEMBL2944533 0.85 MAPT (0.69) RAPGEF4NPC1RAB9AMEN1KMT2A
SCHEMBL20829079 0.85 RAPGEF4 (0.42) RAPGEF4NPC1RAB9AMEN1KMT2A
SCHEMBL11587472 0.82 CDC25B (0.63) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL1922073 0.81 NPSR1 (0.72) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL9183066 0.81 MAPT (0.69) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL18570092 0.80 ALDH1A1 (0.40) RAPGEF4NPC1RAB9AMEN1KMT2A
SCHEMBL1688844 0.80 NPSR1 (0.71) RAPGEF4NPC1RAB9AMEN1KMT2A
SCHEMBL11335085 0.79 TAS2R14 (0.74) MEN1KMT2AMAPTGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139977-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2012-09-05 — — EP claimed
EP-2139977-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2010-01-06 — — EP claimed
WO-2008123940-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-16 — — WO claimed
US-20080248985-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2008-10-09 — — US claimed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 — — EP disclosed
EP-2139977-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2012-09-05 — — EP disclosed
EP-2139977-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2012-09-05 — — EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 — — EP disclosed
US-20100217043-A1 Lubricating compositions containing ashless catalytic antioxidant additives PATIL ABHIMANYU O 2010-08-26 — — US disclosed
US-20100217043-A1 Lubricating compositions containing ashless catalytic antioxidant additives PATIL ABHIMANYU O 2010-08-26 — — US disclosed
US-20100217043-A1 Lubricating compositions containing ashless catalytic antioxidant additives PATIL ABHIMANYU O 2010-08-26 — — US disclosed
US-7759295-B2 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-07-20 — — US disclosed
WO-2008123940-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-16 — — WO disclosed
US-20080248985-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2008-10-09 — — US disclosed
US-20080248985-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2008-10-09 — — US disclosed
US-20080248985-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2008-10-09 — — US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 — — US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 — — US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 — — EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217043-A1 Lubricating compositions containing ashless catalytic antioxidant additives SOD1, GPX4, GPX1 RAPGEF4 4464/4885NPC1 2870/4885RAB9A 2497/4885
US-20080248985-A1 Lubricating compositions containing ashless catalytic antioxidant additives SOD1, GPX4, GPX1 RAPGEF4 4464/4885NPC1 2870/4885RAB9A 2497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.