SCHEMBL2931765

SCHEMBL2931765

Nc1ccccc1Nc1cc(Nc2ccccc2N)cc(Nc2ccccc2N)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.74
GAA P10253 8/20 0.74
KDM4E B2RXH2 7/20 0.74
ALDH1A1 P00352 7/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
LMNA P02545 2/20 0.74
CYP1A2 P05177 1/20 0.74
CYP2D6 P10635 1/20 0.74
CYP2C9 P11712 1/20 0.74
CYP2C19 P33261 1/20 0.74
SMN1; SMN2 Q16637 3/20 0.68
HPGD P15428 2/20 0.68
HSD17B10 Q99714 2/20 0.68
TP53 P04637 1/20 0.68
APP P05067 1/20 0.68
ALOX15 P16050 1/20 0.68
SNCA P37840 1/20 0.68
BLM P54132 1/20 0.68
TDP1 Q9NUW8 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7166997 0.91 MAPT (0.75) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL9183066 0.89 MAPT (0.69) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL4607773 0.87 MAPT (0.86) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL217480 0.85 MAPT (1.00) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29388147 0.85 MAPT (1.00) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL2944533 0.85 MAPT (0.69) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL2508112 0.85 MAPT (0.61) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL2677107 0.84 MAPT (0.71) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL17533031 0.83 MAPT (0.64) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL6576141 0.83 MAPT (0.95) MAPTGAAKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2224790-B1 Light emitting element and azole compound UDC IRELAND LTD (IE) 2013-01-02 EP disclosed
US-7838131-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2010-11-23 US disclosed
EP-1175128-B1 Light emitting element and azole compound FUJIFILM CORP (JP) 2010-09-22 EP disclosed
EP-2224790-A1 Light emitting element and azole compound Fujifilm Corporation (JP) 2010-09-01 EP disclosed
US-20100044638-A1 1,3,5-Tri((2-(methyl-)benzimidazol-1-yl)-)benzene; OLED'shaving a light emission maximum wavelength of 500 nm or less wherein the minimum excitation triplet energy level of the host material is higher than the minimum excitation triplet energy level of the light emitting material FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-7632579-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2009-12-15 US disclosed
US-20050260452-A1 Light emitting element and azole compound FUJI PHOTO FILM CO., LTD. 2005-11-24 US disclosed
US-6962755-B2 Light emitting element and azole compound FUJI PHOTO FILM CO., LTD. (JP) 2005-11-08 US disclosed
US-20020028329-A1 Light emitting element and azole compound FUJI PHOTO FILM CO., LTD. 2002-03-07 US disclosed
EP-1175128-A2 Light emitting element and azole compound FUJI PHOTO FILM CO., LTD. (JP) 2002-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028329-A1 Light emitting element and azole compound CRY1, CRY2, EML4 MAPT 207/4885GAA 4304/4885KDM4E 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.