SCHEMBL29445618

SCHEMBL29445618

CC(C)(C)SSC[C@@H](C=O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.53
KMT2A Q03164 2/20 0.45
MDM4 O15151 1/20 0.43
TP53 P04637 1/20 0.43
EPHX2 P34913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12510996 1.00 CASP3 (0.53) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL13253077 0.86 CASP3 (0.48) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL1739174 0.85 MDM4 (0.54) CASP3MDM4TP53
SCHEMBL10020438 0.85 MDM4 (0.54) CASP3MDM4TP53
SCHEMBL27129147 0.84 MDM4 (0.49) CASP3KMT2AMDM4TP53
SCHEMBL27008576 0.84 MDM4 (0.49) CASP3KMT2AMDM4TP53
SCHEMBL6517147 0.84 CASP3 (0.47) CASP3KMT2AMDM4TP53
SCHEMBL10187000 0.84 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL13570148 0.84 CASP3 (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL30112677 0.83 CASP3 (0.55) CASP3KMT2AMDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492225-B2 Melanocyte-regulating peptides IDP DISCOVERY PHARMA, S.L. (ES) 2025-12-09 US disclosed
EP-4532513-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2025-04-09 EP disclosed
CN-119451974-A Cyclic peptides having antibacterial activity against Multiple Drug Resistant (MDR) pathogens 巴塞罗那全球健康研究所私人基金会 2025-02-14 CN disclosed
US-20240294573-A1 CONSTRAINED PEPTIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-09-05 US disclosed
US-20240083943-A1 VEGF-REGULATING PEPTIDES IDP DISCOVERY PHARMA, S.L. (ES) 2024-03-14 US disclosed
WO-2023227771-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2023-11-30 WO disclosed
EP-4271480-A1 VEGF-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2023-11-08 EP disclosed
CN-116964074-A Peptides that modulate VEGF IDP研发制药有限公司 2023-10-27 CN disclosed
CN-111263768-B anticancer peptides IDP研发制药有限公司 2023-10-13 CN disclosed
EP-3159352-B1 STITCHED POLYPEPTIDES HARVARD COLLEGE (US) 2023-08-02 EP disclosed
US-11440939-B2 Anticancer peptides IDP DISCOVERY PHARMA, S.L. (ES) 2022-09-13 US disclosed
EP-4039698-A1 PEPTIDES WITH ANTI-CANCER ACTIVITY IDP Discovery Pharma, S.L. (ES) 2022-08-10 EP disclosed
WO-2022144401-A1 VEGF-REGULATING PEPTIDES IDP DISCOVERY PHARMA, S.L. (ES) 2022-07-07 WO disclosed
EP-4023295-A1 VEGF-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2022-07-06 EP disclosed
EP-4007563-A1 MELANOCYTE-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2022-06-08 EP disclosed
US-11352395-B2 Anticancer peptides IDP DISCOVERY PHARMA, S.L. (ES) 2022-06-07 US disclosed
EP-3986914-A1 CONSTRAINED PEPTIDES TearSolutions, Inc. (US) 2022-04-27 EP disclosed
CN-114245800-A Melanocyte regulatory peptides IDP研发制药有限公司 2022-03-25 CN disclosed
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-22 US disclosed
CN-114206916-A Restricted peptides 缇尔索卢森公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492225-B2 Melanocyte-regulating peptides MC1R, MITF, MCHR1 CASP3 4704/4885KMT2A 995/4885MDM4 450/4885
US-11440939-B2 Anticancer peptides NGLY1, SLC1A5, SSTR5 CASP3 1352/4885KMT2A 2923/4885MDM4 377/4885
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries TP53, MDM2, MDM4 CASP3 2615/4885KMT2A 3182/4885MDM4 3/4885
US-20240294573-A1 CONSTRAINED PEPTIDES IAPP, NGLY1, VIP CASP3 1870/4885KMT2A 4628/4885MDM4 2200/4885
US-11352395-B2 Anticancer peptides PNISR, NGLY1, SLC1A5 CASP3 2512/4885KMT2A 1904/4885MDM4 265/4885
US-20240083943-A1 VEGF-REGULATING PEPTIDES VEGFA, FLT4, FLT1 CASP3 3795/4885KMT2A 3448/4885MDM4 662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.