SCHEMBL29445680

SCHEMBL29445680

NCCCNc1ccc2ccc(NCCCN)nc2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.56
STK17A Q9UEE5 1/20 0.44
IRAK4 Q9NWZ3 1/20 0.43
HRH4 Q9H3N8 2/20 0.41
PIM1 P11309 2/20 0.40
PIM2 Q9P1W9 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
TLR8 Q9NR97 2/20 0.39
NUDT1 P36639 1/20 0.39
CHEK1 O14757 2/20 0.37
CDK7 P50613 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12198652 1.00 HRH3 (0.56) HRH3STK17AIRAK4HRH4PIM1
SCHEMBL16019054 0.94 HRH3 (0.50) HRH3STK17AIRAK4HRH4PIM1
SCHEMBL16019055 0.91 TLR8 (0.51) HRH3STK17AIRAK4HRH4MEN1
SCHEMBL16019053 0.86 TLR8 (0.46) HRH3TLR8
SCHEMBL2907513 0.84 HRH3 (0.43) HRH3STK17AIRAK4HRH4PIM1
SCHEMBL5943488 0.78 NCF1 (0.52) HRH3IRAK4HRH4PIM1PIM2
SCHEMBL29625898 0.74 SYK (0.44) HRH3IRAK4MEN1ALDH1A1HPGD
SCHEMBL31648525 0.74 TLR8 (0.49) HRH3TLR8
SCHEMBL8354796 0.73 NCF1 (0.50) HRH3HRH4HPGDHSD17B10
SCHEMBL31742466 0.72 HRH3 (0.51) HRH3STK17AIRAK4HRH4PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115801664-B Method and apparatus for an alternative communication path via a connected network 霍尼韦尔国际公司 2025-04-29 CN claimed
CN-117408548-A Evaluation index construction method and system for enterprise green performance system 合肥工业大学 2024-01-16 CN claimed
CN-115914138-A Data transmission method, device and equipment and dual-connection PRP node 北京东土军悦科技有限公司 2023-04-04 CN claimed
CN-115801664-A Method and apparatus for alternative communication paths via a connected network 霍尼韦尔国际公司 2023-03-14 CN claimed
CN-115759711-A Comprehensive evaluation method and system for demand response execution effect oriented to load management 国网江苏省电力有限公司营销服务中心 2023-03-07 CN claimed
CN-112898580-B Sequencing reagent 安序源生物科技(深圳)有限公司 2022-11-08 CN claimed
CN-114104500-A Improve photomask inner box of fastening power and remove with outer box PMC国际株式会社 2022-03-01 CN claimed
EP-4730741-A1 NETWORK INTERFACE AND METHOD FOR PROCESSING ETHERNET NETWORK FRAMES NXP B.V. (NL) 2026-04-22 EP disclosed
US-20260106823-A1 NETWORK INTERFACE AND METHOD FOR PROCESSING ETHERNET NETWORK FRAMES NXP BV (NL) 2026-04-16 US disclosed
US-12571045-B2 Paper-based, nucleic acid-detecting kit and method for analysis of PCR amplicon THE ASAN FOUNDATION (KR) 2026-03-10 US disclosed
US-20260046308-A1 PREVENTING SUPERVISION FRAME INJECTION ATTACKS IN REPLICATION NETWORKS CISCO TECH INC (US) 2026-02-12 US disclosed
US-20250379812-A1 LAYER 3 ROUTER AND METHOD FOR ROUTING PRP FRAMES SIEMENS CANADA LIMITED (CA) 2025-12-11 US disclosed
CN-115914138-B Data transmission method, device, equipment and dual-connection PRP node 北京东土军悦科技有限公司 2025-08-05 CN disclosed
US-11411807-B2 Method and system for detecting and mitigating cabling issues with devices in substation automation systems ABB SCHWEIZ AG (CH) 2022-08-09 US disclosed
US-20220205811-A1 METERING ASSEMBLY, SWITCHBOARD CASE, ADAPTER CRADLE AND METHOD OF USE EI ELECTRONICS LLC D/B/A ELECTRO INDUSTRIES/GAUGE TECH 2022-06-30 US disclosed
US-20220195543-A1 PAPER-BASED, NUCLEIC ACID-DETECTING KIT AND METHOD FOR ANALYSIS OF PCR AMPLICON UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION (KR) 2022-06-23 US disclosed
CN-111711583-B Switch supporting configuration of multiple redundancy protocols and transformer substation network system 广东电网有限责任公司 2022-06-14 CN disclosed
CN-112311618-B Test method and test equipment of network switching equipment 北京东土科技股份有限公司 2022-05-17 CN disclosed
US-20220131741-A1 METHOD AND SYSTEM FOR DETECTING AND MITIGATING CABLING ISSUES WITH DEVICES IN SUBSTATION AUTOMATION SYSTEMS HITACHI ENERGY LTD (CH) 2022-04-28 US disclosed
US-11300424-B2 Metering assembly, switchboard case, adapter cradle and method of use ELECTRO INDUSTRIES/GAUGETECH (US) 2022-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260106823-A1 NETWORK INTERFACE AND METHOD FOR PROCESSING ETHERNET NETWORK FRAMES GET3, TAP1, AXIN2 HRH3 4616/4885STK17A 4819/4885IRAK4 2084/4885
US-20260046308-A1 PREVENTING SUPERVISION FRAME INJECTION ATTACKS IN REPLICATION NETWORKS PDGFRB, PRF1, PRLHR HRH3 2762/4885STK17A 3513/4885IRAK4 1831/4885
US-12571045-B2 Paper-based, nucleic acid-detecting kit and method for analysis of PCR amplicon PCNA, RNGTT, ACR HRH3 4506/4885STK17A 1330/4885IRAK4 313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.