Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | PPP1R15A | O75807 | 1/20 | 1.00 |
| ▸ | MELK | Q14680 | 1/20 | 1.00 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | GRIN2D | O15399 | 13/20 | 0.74 |
| ▸ | GRIN3B | O60391 | 13/20 | 0.74 |
| ▸ | GRIN1 | Q05586 | 13/20 | 0.74 |
| ▸ | GRIN2A | Q12879 | 13/20 | 0.74 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.74 |
| ▸ | GRIN2C | Q14957 | 13/20 | 0.74 |
| ▸ | GRIN3A | Q8TCU5 | 13/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872248 | 1.00 | NPSR1 (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5703102 | 0.98 | NPSR1 (0.97) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Acetic Acid SCHEMBL29736263 | 0.91 | NPSR1 (0.82) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL29445212 | 0.85 | GRIN2D (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL15884162 | 0.85 | GRIN2D (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Guanabenz SCHEMBL15390 | 0.79 | TAAR1 (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Guanabenz SCHEMBL219392 | 0.79 | TAAR1 (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5703211 | 0.78 | GRIN2D (0.73) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL30275282 | 0.75 | L3MBTL1 (0.59) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL6847216 | 0.75 | L3MBTL1 (0.59) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966344-B1 | KINASE SCREENING ASSAYS | UNIV NEWCASTLE (GB) | 2025-06-25 | — | — | EP | claimed |
| US-20220213524-A1 | KINASE SCREENING ASSAYS | THE UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2022-07-07 | — | — | US | claimed |
| EP-3966344-A1 | KINASE SCREENING ASSAYS | University of Newcastle Upon Tyne (GB) | 2022-03-16 | — | — | EP | claimed |
| EP-3966344-B1 | KINASE SCREENING ASSAYS | UNIV NEWCASTLE (GB) | 2025-06-25 | — | — | EP | disclosed |
| CN-117295505-A | Modulation of the milk philin subfamily 3 member A1 (BTN 3A1, CD 277) | 加利福尼亚大学董事会 | 2023-12-26 | — | — | CN | disclosed |
| US-20220213524-A1 | KINASE SCREENING ASSAYS | THE UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2022-07-07 | — | — | US | disclosed |
| EP-3966344-A1 | KINASE SCREENING ASSAYS | University of Newcastle Upon Tyne (GB) | 2022-03-16 | — | — | EP | disclosed |