Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | PPP1R15A | O75807 | 1/20 | 1.00 |
| ▸ | MELK | Q14680 | 1/20 | 1.00 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | GRIN2D | O15399 | 13/20 | 0.74 |
| ▸ | GRIN3B | O60391 | 13/20 | 0.74 |
| ▸ | GRIN1 | Q05586 | 13/20 | 0.74 |
| ▸ | GRIN2A | Q12879 | 13/20 | 0.74 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.74 |
| ▸ | GRIN2C | Q14957 | 13/20 | 0.74 |
| ▸ | GRIN3A | Q8TCU5 | 13/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447252 | 1.00 | NPSR1 (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5703102 | 0.98 | NPSR1 (0.97) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Acetic Acid SCHEMBL29736263 | 0.91 | NPSR1 (0.82) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL29445212 | 0.85 | GRIN2D (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL15884162 | 0.85 | GRIN2D (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Guanabenz SCHEMBL15390 | 0.79 | TAAR1 (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Guanabenz SCHEMBL219392 | 0.79 | TAAR1 (1.00) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5703211 | 0.78 | GRIN2D (0.73) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL30275282 | 0.75 | L3MBTL1 (0.59) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 | |
| SCHEMBL6847216 | 0.75 | L3MBTL1 (0.59) | NPSR1PPP1R15AMELKPPP1R15BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024263569-A1 | REGULATION OF BUTYROPHILIN 2A1 (BTN2A1) | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2024-12-26 | — | — | WO | disclosed |
| US-20240115705-A1 | Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240115705-A1 | Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277) | BTN3A1, BTF3, CD274 | NPSR1 3535/4885PPP1R15A 27/4885MELK 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.