Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604385 | 0.78 | OPRM1 (0.82) | OPRM1 | |
| SCHEMBL28617394 | 0.78 | OPRM1 (0.56) | SIGMAR1OPRM1 | |
| SCHEMBL13929351 | 0.78 | L3MBTL1 (0.69) | L3MBTL1SIGMAR1 | |
| SCHEMBL12074098 | 0.75 | L3MBTL1 (0.75) | L3MBTL1SIGMAR1 | |
| SCHEMBL28594954 | 0.75 | OPRM1 (0.78) | OPRM1 | |
| SCHEMBL13929228 | 0.75 | ACHE (0.49) | L3MBTL1SIGMAR1 | |
| SCHEMBL4217001 | 0.75 | SIGMAR1 (0.57) | L3MBTL1SIGMAR1 | |
| SCHEMBL29448587 | 0.73 | OPRM1 (0.69) | L3MBTL1OPRM1 | |
| SCHEMBL28606816 | 0.73 | OPRM1 (0.74) | OPRM1 | |
| SCHEMBL28609565 | 0.73 | OPRM1 (0.92) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |