SCHEMBL2944958

SCHEMBL2944958

CC(C)c1ccc(Oc2ccc(N)cc2)c(Cc2cc(C(C)C)ccc2Oc2ccc(N)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTR2A P28223 2/20 0.40
SLC6A4 P31645 2/20 0.40
TEAD4 Q15561 1/20 0.39
KCNH2 Q12809 1/20 0.39
MAPT P10636 5/20 0.39
GAA P10253 3/20 0.39
MAPK1 P28482 2/20 0.39
HTT P42858 2/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
MITF O75030 1/20 0.38
GFER P55789 1/20 0.38
NLRP1 Q9C000 1/20 0.38
NOD2 Q9HC29 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8158498 0.81 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL2945590 0.80 GABRA1 (0.41) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL3022060 0.80 TEAD4 (0.55) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL8153389 0.79 PPARG (0.39) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL8154185 0.77 HTR2A (0.36) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL21925217 0.77 MAPT (0.50) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL22966319 0.75 ALDH1A1 (0.46) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL22069710 0.75 PDE7A (0.54) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL31457237 0.75 HTR2A (0.48) ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2
SCHEMBL2945587 0.75 CYP19A1 (0.44) ALDH1A1SMN1; SMN2HTR2ASLC6A4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7751020-B2 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. (JP) 2010-07-06 US disclosed
US-7643119-B2 Liquid crystal display device having improved spacers HITACHI, LTD. (JP) 2010-01-05 US disclosed
US-20090051864-A1 Liquid crystal display device having improved spacers HITACHI, LTD. 2009-02-26 US disclosed
US-20070040984-A1 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. 2007-02-22 US disclosed
US-7167228-B2 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. (JP) 2007-01-23 US disclosed
US-7050140-B2 Liquid crystal display device with spacers formed on a planarizing film disposed over color filters HITACHI, LTD. (JP) 2006-05-23 US disclosed
US-7012668-B2 Method of measuring AC residual image in a liquid crystal display device HITACHI, LTD. (JP) 2006-03-14 US disclosed
US-20050200795-A1 Liquid crystal display device IPS ALPHA SUPPORT CO., LTD. (JP) 2005-09-15 US disclosed
US-20040257483-A1 LIQUID CRYSTAL DISPLAY DEVICE WITH SPACERS FORMED ON A PLANARIZING FILM DISPOSED OVER COLOR FILTERS HITACHI, LTD. 2004-12-23 US disclosed
US-6798486-B2 Liquid crystal display device with spacers formed on a planarizing film disposed over color filters HITACHI, LTD. (JP) 2004-09-28 US disclosed
US-20030151716-A1 Liquid crystal display device HITACHI, LTD. 2003-08-14 US disclosed
US-6583846-B1 Liquid crystal display device with spacer covered with an electrode HITACHI, LTD. (JP) 2003-06-24 US disclosed
US-20030020864-A1 Liquid crystal display device HITACHI, LTD. 2003-01-30 US disclosed
EP-1156363-A1 LIQUID CRYSTAL DISPLAY ELEMENT Hitachi, Ltd. (JP) 2001-11-21 EP disclosed