Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154185 | 0.92 | HTR2A (0.36) | PPARGHTR2ASLC6A4ALDH1A1MAPT | |
| SCHEMBL8158498 | 0.88 | ALDH1A1 (0.41) | HTR2ASLC6A4ALDH1A1MAPTMEN1 | |
| SCHEMBL31457250 | 0.85 | HTR2A (0.49) | HTR2ASLC6A4ALDH1A1MAPTMEN1 | |
| SCHEMBL8581645 | 0.81 | CYP19A1 (0.45) | ALDH1A1TAAR1RAB9AACACB | |
| SCHEMBL8578415 | 0.79 | CYP19A1 (0.42) | HTR2ASLC6A4ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8157883 | 0.79 | CYP19A1 (0.42) | PPARGHTR2ASLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL2944958 | 0.79 | ALDH1A1 (0.41) | HTR2ASLC6A4ALDH1A1MAPTMEN1 | |
| SCHEMBL8153557 | 0.78 | TDP1 (0.47) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2515877 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7609083 | 0.77 | RAB9A (0.49) | PPARGHTR2ASLC6A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700532-B1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | AVENTIS RES & TECH GMBH & CO (DE) | 2000-03-29 | — | — | EP | disclosed |
| EP-0604885-B1 | Liquid crystal display device | HOECHST AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5656340-A | Liquid crystal display device | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0700532-A1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-13 | — | — | EP | disclosed |
| EP-0690334-A2 | Liquid crystal display device | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| US-5437813-A | A thin alignment layer comprising an aromatic polyamide-polysiloxane block homo- or copolymer with different content of polysiloxane to adjust optical pretilt angle | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| WO-1994028458-A1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |
| EP-0604885-A1 | Liquid crystal display device | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-06 | — | — | EP | disclosed |
| US-5037862-A | Excellent mechanical stability in printing | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4954612-A | ORIENTATION CONTROL FOR LIQUID CRYSTAL DISPLAY | HITACHI CHEMICAL CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4791157-A | REACTING TRIMELLITIC ACID WITH AROMATIC DIAMINE WITH ETHER GROUPS | HITACHI CHEMICAL CO. (JP) | 1988-12-13 | — | — | US | disclosed |
| US-4758875-A | Resin encapsulated semiconductor device | HITACHI, LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0183694-A4 | HERPES SIMPLEX TREATMENT. | MEDICAL TECHNOLOGY CORP (US) | 1987-06-16 | — | — | EP | disclosed |
| EP-0183694-A1 | HERPES SIMPLEX TREATMENT | MEDITECH PHARMACEUTICALS, INC. (US) | 1986-06-11 | — | — | EP | disclosed |
| WO-1986000016-A1 | HERPES SIMPLEX TREATMENT | MEDICAL TECHNOLOGY CORP. OF AMERICA, INC. (US) | 1986-01-03 | — | — | WO | disclosed |