SCHEMBL29450325

SCHEMBL29450325

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 4/20 0.53
▸ OPRD1 P41143 4/20 0.53
▸ KISS1R Q969F8 10/20 0.53
▸ OPRK1 P41145 1/20 0.48
▸ F2 P00734 4/20 0.47
▸ VIPR1 P32241 1/20 0.47
▸ VIPR2 P41587 1/20 0.47
▸ GLP1R P43220 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31275672 0.91 KISS1R (0.47) OPRM1OPRD1KISS1RF2
SCHEMBL15272531 0.90 OPRM1 (0.50) OPRM1OPRD1KISS1R
SCHEMBL15272522 0.90 OPRM1 (0.50) OPRM1OPRD1KISS1R
SCHEMBL29519563 0.87 OPRM1 (0.50) OPRM1OPRD1KISS1ROPRK1
SCHEMBL30350806 0.87 OPRM1 (0.57) OPRM1OPRD1KISS1ROPRK1
SCHEMBL31307241 0.85 BACE1 (0.57) —
SCHEMBL29449897 0.84 BACE1 (0.47) OPRM1OPRD1KISS1R
SCHEMBL30198105 0.84 KISS1R (0.46) OPRM1OPRD1KISS1ROPRK1GLP1R
SCHEMBL29705780 0.84 OPRD1 (0.54) OPRM1OPRD1OPRK1
SCHEMBL30874946 0.84 GLP1R (0.52) OPRD1KISS1RF2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114075264-B Polypeptide for promoting swine organism to generate African swine fever virus antigen specific immune response and application thereof 中国农业科学院兰州兽医研究所 2023-06-16 — — CN disclosed
CN-114075264-A Polypeptide for promoting swine organisms to generate African swine fever virus antigen specific immune response and application thereof 中国农业科学院兰州兽医研究所 2022-02-22 — — CN disclosed
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