Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29451106 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| SCHEMBL7182044 | 0.88 | GAA (0.55) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| SCHEMBL3782361 | 0.86 | GAA (0.53) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| SCHEMBL6664968 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| SCHEMBL29451094 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| SCHEMBL19461248 | 0.85 | GAA (0.52) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| Hydrochloric Acid SCHEMBL22834182 | 0.85 | MEN1 (0.58) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| SCHEMBL28700663 | 0.85 | GAA (0.52) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| Hydrochloric Acid SCHEMBL29451098 | 0.85 | MEN1 (0.58) | ALDH1A1KDM4EMAPTGAACYP3A4 | |
| Hydrochloric Acid SCHEMBL19461409 | 0.83 | GAA (0.50) | ALDH1A1KDM4EMAPTGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619837-A | Preparation method of 2-trifluoromethyl-4-aminobenzoic acid | 江西金丰药业有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-116178689-A | Liquid crystal polymer and preparation method and application thereof | 深圳大学 | 2023-05-30 | — | — | CN | claimed |
| CN-109824892-B | Polyimide copolymer precursor, polyimide, and method for producing polyimide film | 武汉柔显科技股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-109824892-A | The preparation method of polyimide copolymer precursor, polyimides and Kapton | 武汉柔显科技股份有限公司 | 2019-05-31 | — | — | CN | claimed |
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | disclosed |
| CN-118619837-B | Preparation method of 2-trifluoromethyl-4-aminobenzoic acid | 江西金丰药业有限公司 | 2025-09-05 | — | — | CN | disclosed |
| CN-118619837-B | Preparation method of 2-trifluoromethyl-4-aminobenzoic acid | 江西金丰药业有限公司 | 2025-09-05 | — | — | CN | disclosed |
| EP-4568951-A1 | HETEROCYCLIC AMIDE AND UREA COMPOUNDS AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2025-06-18 | — | — | EP | disclosed |
| EP-4267574-B1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| US-12275717-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | AJAX THERAPEUTICS, INC. (US) | 2025-04-15 | — | — | US | disclosed |
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | ROCHE SEQUENCING SOLUTIONS INC (US) | 2025-03-06 | — | — | US | disclosed |
| CN-118619837-A | Preparation method of 2-trifluoromethyl-4-aminobenzoic acid | 江西金丰药业有限公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2007098089-A2 | TREATMENT OF HYPERPROLIFERATIVE DISEASES WITH METHOTREXATE N-OXIDE AND ANALOGS | NOVACEA, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007042299-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS SYK INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-04-19 | — | — | WO | disclosed |
| US-20060160803-A1 | Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | US | disclosed |
| WO-2006076706-A1 | CINNAMIDE AND HYDROCINNAMIDE DERIVATIVES WITH RAF-KINASE INHIBITORY ACTIVITY | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0831845-A4 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0831845-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | Elizanor Biopharmaceuticals, Inc. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275717-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | JAK2, JAK3, STAT5B | ALDH1A1 3735/4885KDM4E 444/4885MAPT 4844/4885 |
| US-20060160803-A1 | Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity | MAP3K21, HIPK4, MAP3K20 | ALDH1A1 2863/4885KDM4E 1705/4885MAPT 3192/4885 |
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | POLN, POLB, POLRMT | ALDH1A1 3208/4885KDM4E 934/4885MAPT 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.