Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694508 | 0.82 | CYP2C9 (0.67) | TDP1MEN1POLBKMT2AMAPT | |
| SCHEMBL3154100 | 0.82 | POLB (0.67) | TDP1MEN1POLBKMT2AMAPT | |
| SCHEMBL25271016 | 0.81 | ALDH1A1 (0.42) | SMN1; SMN2POLBKDM4E | |
| Hydrochloric Acid SCHEMBL6417883 | 0.81 | SLC6A2 (0.44) | MEN1POLBKMT2AMAPTCYP2C9 | |
| SCHEMBL92331 | 0.81 | L3MBTL1 (0.56) | MEN1POLBKMT2AMAPTCYP2C9 | |
| SCHEMBL3033992 | 0.80 | POLB (0.68) | SMN1; SMN2TDP1MEN1POLBKMT2A | |
| SCHEMBL3906515 | 0.80 | SLC6A2 (0.47) | MEN1POLBKMT2AMAPTCYP2C9 | |
| Bromide SCHEMBL28426487 | 0.80 | L3MBTL1 (0.54) | MEN1POLBKMT2AMAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL4768580 | 0.80 | L3MBTL1 (0.54) | MEN1POLBKMT2AMAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL6886546 | 0.79 | SLC6A2 (0.46) | MEN1POLBKMT2AMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250058-B | PPAR agonists and their use in the treatment of Alzheimer's disease and other diseases | 上海怡立舍生物技术有限公司 | 2022-02-11 | — | — | CN | disclosed |