Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046747 | 1.00 | LMNA (0.34) | LMNATP53GPR55CNR2NPC1 | |
| SCHEMBL29453312 | 1.00 | LMNA (0.34) | LMNATP53GPR55CNR2NPC1 | |
| SCHEMBL1046953 | 0.92 | LMNA (0.34) | LMNATP53GPR55CNR2NPC1 | |
| SCHEMBL13930732 | 0.89 | HTT (0.32) | LMNATP53ALDH1A1MEN1POLB | |
| SCHEMBL6400700 | 0.86 | LMNA (0.31) | LMNATP53ALDH1A1MAPT | |
| SCHEMBL1046720 | 0.86 | PDGFRB (0.32) | LMNAGPR55NPC1GFERMEN1 | |
| SCHEMBL29453301 | 0.86 | PDGFRB (0.32) | LMNAGPR55NPC1GFERMEN1 | |
| SCHEMBL1042878 | 0.85 | DRD2 (0.34) | ALDH1A1GAA | |
| SCHEMBL29453305 | 0.85 | DRD2 (0.34) | ALDH1A1GAA | |
| SCHEMBL9882509 | 0.85 | HTR1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11256002-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2022-02-22 | — | — | US | disclosed |