SCHEMBL6400700

SCHEMBL6400700

C=C(C)C(=O)OCCNC(=O)OCCOc1ccc(C2(c3ccccc3)C=Cc3c4c(c5ccc(OC)cc5c3O2)-c2ccc(OC)cc2C4(C)C)cc1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALK Q9UM73 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1011066 0.96 FAAH (0.31)
SCHEMBL6400695 0.92 ALK (0.32) LMNATP53ALDH1A1ALKKDM4E
SCHEMBL1045930 0.90 ALDH1A1 (0.30) ALDH1A1
SCHEMBL29453328 0.90 ALDH1A1 (0.30) ALDH1A1
SCHEMBL14198674 0.90 SMN1; SMN2 (0.31)
SCHEMBL14198676 0.90 POLB (0.32) MAPT
SCHEMBL1011065 0.88 FAAH (0.31)
SCHEMBL24404052 0.86 POLB (0.31)
SCHEMBL29453307 0.86 LMNA (0.34) LMNATP53ALDH1A1MAPT
SCHEMBL29453312 0.86 LMNA (0.34) LMNATP53ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7364291-B2 Contact lenses with light blocking rings JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-04-29 US disclosed
US-7364291-B2 Contact lenses with light blocking rings JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-04-29 US disclosed
US-20080002147-A1 CONTACT LENSES WITH LIGHT BLOCKING RINGS JOHNSON & JOHNSON VISION CARE, INC. 2008-01-03 US disclosed
US-20080002147-A1 CONTACT LENSES WITH LIGHT BLOCKING RINGS JOHNSON & JOHNSON VISION CARE, INC. 2008-01-03 US disclosed
WO-2008003012-A2 CONTACT LENSES WITH LIGHT BLOCKING RINGS JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-01-03 WO disclosed
US-20050258408-A1 Photochromic contact lenses and methods for their production MOLOCK FRANK F 2005-11-24 US disclosed