SCHEMBL29454111

SCHEMBL29454111

Cc1cccc(N(C)c2cc(F)cc(N)c2C)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.39
CSF1R P07333 5/20 0.36
SIGMAR1 Q99720 2/20 0.36
EGFR P00533 4/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.34
DHFR P00374 1/20 0.33
RECQL P46063 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232258 1.00 ACHE (0.39) ACHECSF1RSIGMAR1EGFRSMN1; SMN2
SCHEMBL31723240 1.00 ACHE (0.39) ACHECSF1RSIGMAR1EGFRSMN1; SMN2
SCHEMBL31723221 0.89 ABCG2 (0.38) ACHEF2F10DHFRSLC6A2
SCHEMBL22232350 0.89 ABCG2 (0.38) ACHEF2F10DHFRSLC6A2
SCHEMBL29454066 0.89 ABCG2 (0.38) ACHEF2F10DHFRSLC6A2
SCHEMBL31723210 0.86 CHKA (0.37) EGFRF2F10MAPTDHFR
SCHEMBL29454049 0.86 CHKA (0.37) EGFRF2F10MAPTDHFR
SCHEMBL29454126 0.85 EGFR (0.41) CSF1REGFRF2F10MAPT
SCHEMBL29454047 0.83 MTNR1A (0.40) ACHESMN1; SMN2HSD17B1HSD17B2ALDH1A1
SCHEMBL31723244 0.83 NOS1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US claimed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS ACHE 169/4885CSF1R 3613/4885SIGMAR1 3215/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS ACHE 2049/4885CSF1R 4415/4885SIGMAR1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.