SCHEMBL2945418

SCHEMBL2945418

CC(=O)OC1=CCc2ccccc2C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 2/20 0.37
ELANE P08246 1/20 0.37
ESR1 P03372 1/20 0.37
ITGB3 P05106 1/20 0.37
ITGA2B P08514 1/20 0.37
HMGB1 P09429 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
GGT1 P19440 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
BLM P54132 1/20 0.37
NAPRT Q6XQN6 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NOTUM Q6P988 2/20 0.36
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4442002 0.75 MAOA (0.45) ALDH1A1KDM4EHSD17B10ELANEESR1
SCHEMBL11593730 0.75 DRD1 (0.36) ALDH1A1KDM4EHPGDPTGS2MAPT
SCHEMBL20094561 0.74 LMNA (0.39) ALDH1A1KDM4EHSD17B10ELANEESR1
SCHEMBL6480675 0.74 MTNR1A (0.34)
SCHEMBL10353430 0.73 GLA (0.33) ALDH1A1KDM4EHSD17B10HPGDTDP1
SCHEMBL6490008 0.73 MTNR1A (0.35) TSHRKMT2A
SCHEMBL11595680 0.72 ALDH1A1 (0.40) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL7633782 0.71 ALDH1A1 (0.41) ALDH1A1KDM4EHSD17B10ELANEESR1
SCHEMBL7080275 0.71 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10ELANEESR1
SCHEMBL31648648 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2625255-A2 MIXTURE OF FRAGRANCE COMPOUNDS Symrise AG (DE) 2013-08-14 EP disclosed
WO-2010142815-A2 MIXTURE OF FRAGRANCE COMPOUNDS SYMRISE GMBH & CO. KG (DE) 2010-12-16 WO disclosed