Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 9/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308305 | 1.00 | TRPV1 (0.58) | TRPV1MAPK1GPR139CYP3A4CYP2D6 | |
| SCHEMBL306501 | 1.00 | TRPV1 (0.58) | TRPV1MAPK1GPR139CYP3A4CYP2D6 | |
| SCHEMBL306502 | 1.00 | TRPV1 (0.58) | TRPV1MAPK1GPR139CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL29454378 | 0.99 | TRPV1 (0.57) | TRPV1MAPK1GPR139CYP3A4CYP2D6 | |
| SCHEMBL2692974 | 0.92 | TRPV1 (0.68) | TRPV1MAPK1GPR139CYP3A4CYP2D6 | |
| SCHEMBL14291771 | 0.90 | TRPV1 (0.58) | TRPV1MAPK1GPR139CYP3A4CYP2D6 | |
| SCHEMBL2694475 | 0.89 | TRPV1 (0.59) | TRPV1MAPK1GPR139ARENPP2 | |
| SCHEMBL2695127 | 0.89 | TRPV1 (0.59) | TRPV1MAPK1GPR139ARENPP2 | |
| SCHEMBL307032 | 0.89 | TRPV1 (0.66) | TRPV1MAPK1GPR139CYP3A4CYP2D6 | |
| SCHEMBL306518 | 0.89 | TRPV1 (0.58) | TRPV1MAPK1GPR139CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089550-A1 | CRYSTALLINE FORMS OF (S)-2-(7-CYANO-1H-BENZIMIDAZOL-1 YL)-N-{1-[4-(1-CYANO-1-METHYLETHYL)PHENYL]ETHYL}ACETAMIDE | NEOMED INSTITUTE - INSTITUT NEOMED (CA) | 2022-03-24 | — | — | US | claimed |
| EP-3908574-A4 | CRYSTALLINE FORMS OF (S)-2-(7-CYANO-1H-BENZIMIDAZOL-1 YL)- N-{1-[4-(1-CYANO-1-METHYLETHYL)PHENYL]ETHYL}ACETAMIDE | Neomed Institute (CA) | 2022-10-26 | — | — | EP | disclosed |
| US-20220089550-A1 | CRYSTALLINE FORMS OF (S)-2-(7-CYANO-1H-BENZIMIDAZOL-1 YL)-N-{1-[4-(1-CYANO-1-METHYLETHYL)PHENYL]ETHYL}ACETAMIDE | NEOMED INSTITUTE - INSTITUT NEOMED (CA) | 2022-03-24 | — | — | US | disclosed |
| US-20220089550-A1 | CRYSTALLINE FORMS OF (S)-2-(7-CYANO-1H-BENZIMIDAZOL-1 YL)-N-{1-[4-(1-CYANO-1-METHYLETHYL)PHENYL]ETHYL}ACETAMIDE | NEOMED INSTITUTE - INSTITUT NEOMED (CA) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089550-A1 | CRYSTALLINE FORMS OF (S)-2-(7-CYANO-1H-BENZIMIDAZOL-1 YL)-N-{1-[4-(1-CYANO-1-METHYLETHYL)PHENYL]ETHYL}ACETAMIDE | ACMSD, AMY1A, ACACA | TRPV1 2314/4885MAPK1 515/4885GPR139 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.