Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL4047737 | 0.85 | LMNA (0.95) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL19283553 | 0.85 | LMNA (0.95) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL4319576 | 0.85 | LMNA (0.95) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL4319572 | 0.85 | LMNA (0.95) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL5320867 | 0.85 | TSHR (0.73) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL8630179 | 0.84 | LMNA (0.82) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL7529578 | 0.83 | LMNA (0.90) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL7279536 | 0.83 | LMNA (0.90) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL7519719 | 0.83 | LMNA (0.90) | LMNAMAPK1TSHRHPGDCES2 | |
| Mandelic Acid SCHEMBL29777368 | 0.83 | LMNA (1.00) | LMNAMAPK1HPGDCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089550-A1 | CRYSTALLINE FORMS OF (S)-2-(7-CYANO-1H-BENZIMIDAZOL-1 YL)-N-{1-[4-(1-CYANO-1-METHYLETHYL)PHENYL]ETHYL}ACETAMIDE | NEOMED INSTITUTE - INSTITUT NEOMED (CA) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089550-A1 | CRYSTALLINE FORMS OF (S)-2-(7-CYANO-1H-BENZIMIDAZOL-1 YL)-N-{1-[4-(1-CYANO-1-METHYLETHYL)PHENYL]ETHYL}ACETAMIDE | ACMSD, AMY1A, ACACA | LMNA 771/4885MAPK1 515/4885TSHR 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.